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A novel protocol for haploidentical hematopoietic SCT without in vitro T-cell depletion in the treatment of severe acquired aplastic anemia. Bone Marrow Transplant 2012;47:1507-12.
MacNamara, "Hematopoietic stem cell regulation by type I and II interferons in the pathogenesis of acquired aplastic anemia," Frontiers in Immunology, vol.
This is a well-known and distinct variant of acquired aplastic anemia, in which acute hepatitis leads to marrow failure and pancytopenia [22-24].
Acquired Aplastic Anemia: Treatment in developing country.
In a previous study in which we compared hypocellular RA with acquired aplastic anemia, we recommended the use of p53 protein overexpression to differentiate between these disorders since the BM of patients with aplastic anemia did not overexpress p53 protein.
We tested sera from 14 control patients (9 males and 5 females; median age, 25 years; age range, 7-49 years) with aplasia of different origins (acquired aplastic anemia, n = 9; dyskeratosis congenita, n = 2; paroxysmal nocturnal hemoglobinuria, n = 1; leukemia, n = 2) at the time of sampling.
Maciejewski, "Mechanisms of disease--the pathophysiology of acquired aplastic anemia," New England Journal of Medicine, vol.
Dianzani et al., "NOLA1 gene mutations in acquired aplastic anemia," Pediatric Blood and Cancer, vol.
Hematopoietic cell destruction by immunemechanisms in acquired aplastic anemia. Semin Hematol.2000;37:3-14.29.
(7.) Young NS: Acquired aplastic anemia. Ann Intern Med 2002, 136:534-546
Objective: Immunosuppressive treatment (IST) is an alternative for children with acquired aplastic anemia (AA) that do not have HLA-matched donors.
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