aconitine


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a·con·i·tine

(ă-kon'i-tēn),
The exceedingly poisonous active principle (diterpene alkaloid) of Aconitum sp. and Delphinium sp., formerly used as a cardiac sedative and applied externally for neuralgia.

aconitine

/acon·i·tine/ (ah-kon´ĭ-tin) a poisonous alkaloid, the active principle of aconite.

aconitine

(ă-kon′ĭ-tēn″, -tĭn) [ aconite + -ine]
C34H47NO11, a poisonous white crystalline alkaloid that is the active ingredient in aconite.

aconitine

a mixture of alkaloids in aconitumnapellus. Causes abdominal pain, dyspnea, vomiting, diarrhea, cardiac irregularity.
References in periodicals archive ?
Aconitine is contained in the roots of aconite, a blue or yellow flower with green leaves related to the buttercup.
Police cannot release case details for legal reasons but a source said: "Experts say they haven't seen aconitine in Britain for 40 years.
A third cohort of rats in each exposure group was challenged with aconitine to assess sensitivity to arrhythmogenic challenge.
3] exposure significantly reduced the total dose of aconitine necessary to elicit the first ventricular premature beat relative to air-exposed controls (28% and 39%, respectively; p < 0.
Increased sensitivity to aconitine suggests that [O.
Animals exposed to DE had increased sympathetic modulation, prolonged ventricular depolarization, and shortened repolarization periods, and they developed arrhythmia at lower doses of aconitine than controls.
Arrhythmogenesis was assessed 24 hr later by continuous intravenous infusion of aconitine, an arrhythmogenic drug, while heart rate (HR) and electrocardiogram (ECG) were monitored.
Rats exposed to wDE developed arrhythmia at lower doses of aconitine than did controls; the dose was even lower in rats exposed to fDE.