Out of 48 ACDRs reported in prospective study, most common was acneform eruption (25.00%) [Figure-1] followed by fixed drug eruption (FDE) (22.92%).
The most common drugs responsible for ACDRs in prospective study were betamethasone, isoniazid and rifampicin for acneform eruption, while metronidazole and paracetamol for FDE.
Most common was FDE (28.57%) followed by Acneform eruption (11.11%).
The most common drug groups responsible were antimalarial and fluroquinolones for FDE [Figure-4], while acneform eruption was mainly caused by systemic steroids.
FDE (28.57% & 22.92%) and acneform eruption (25% & 11.11%) were the most common ACDRs in prospective study and retrospective study.
In the past, clinicians also have referred to the rash as "acneform
," but use of this term is discouraged because patients may attempt to use common acne treatments (e.g., benzoyl peroxide) for it, which exacerbate the symptoms (Oishi, 2008).