Ibuprofen and diclofenac treatments reduce proliferation of pancreatic acinar cells
upon inflammatory injury and mitogenic stimulation.
Transmission electron micrograph of parotid salivary gland of 30 cm CVRL (141st day) buffalo foetus showing appearance of medium electron dense secretory granules (SG) in the acinar cells
(12) These results strongly suggest NOD1 must be expressed in nonhematopoietic cells, most likely pancreatic acinar cells
, to support pancreatitis development.
The UPR is critical for efficient functioning of the endoplasmic reticulum (ER) in the pancreatic acinar cell
, because the ER provides for the synthesis of cellular components necessary for transporting digestive enzymes manufactured in ER to zymogen granules for storage and for secretion.
Shia et al, "Acinar cell
carcinoma of the pancreas: New genetic and treatment insights into a rare malignancy," Oncologist, vol.
In the early stage of AP, various factors could cause pancreatic acinar cell
injury/death; thus acinar cells
necrosis would increase the intracellular activity of trypsin of pancreatic tissue, releasing various inflammatory mediators and triggering inflammation cascade.
Oxidative injury to isolated rat pancreatic acinar cells
Nobuyoshi Hiraoka at the National Cancer Center Research Institute for advice on diagnosis and for assisting with the immunostaining test for the diagnosis of acinar cell
Huang, "Dachengqi decoction induces pancreatic acinar cell
apoptosis in experimental acute pancreatitis in rats," Journal of Chinese Integrative Medicine, vol.
(8) Other differentials include pancreatoblastoma and acinar cell
carcinoma which can be distinguished by their clinical and morphoimmunophenotypic characteristics.
Dad-of-three Peter was diagnosed with rare Acinar cell
cancer (ACC) after suffering a severe stomach ache and within weeks underwent major surgery to have his spleen and the tumour in his pancreas removed.
But it was only then that the full severity of his illness became clear, when experts discovered his tumour was an extremely rare form of cancer called Acinar cell
cancer (ACC), with between only 10 and 25 cases being diagnosed in the UK each year.