Kamran Azim said that the research on this topic has been done first time in Pakistan which revealed that the increased abundance of acidogenic bacteria
in the oral cavity of diabetic patients.
Although we did not have any biological evidence to conclude our findings, but literature shows that nicotine (or cotinine) decreases the phagocytic activity of monocytes and neutrophils20 and dental caries results from chronic bacterial infection by acidogenic bacteria
. This pathway potentially relates the ETS with dental caries.
This instability occurs in these liquid wastes when a small variation of the acidity produced by acidogenic bacteria
results in a large variation in the pH value that leaves the favourable range for the balance of the microorganisms in the anaerobic digestion (RIBAS et al., 2010; OLIVEIRA-JUNIOR et al., 2012).
Acids in the mouth originate from three main sources: produced in situ by acidogenic bacteria
, ingested extrinsic acids as dietary components and dislocated intrinsic acids through the backflow of gastric contents.
Acidogenesis, when the obtained in the first stage components are decomposed by the acidogenic bacteria
into other organic (acetic, propionic, butanoic acids, alcohols and aldehydes) and inorganic materials ([H.sub.2], C[O.sub.2], [N.sub.2], [H.sub.2]S).
By oxidizing the biomolecules featured in dental diseases, ozone has a severely disruptive effect on cariogenic bacteria, resulting in elimination of acidogenic bacteria
. The strongest naturally occurring acid, produced by acidogenic bacteria
during cariogenesis is pyruvic acid.
Resistant starch acts in a similar way to dietary fibres and stimulates the growth of acidogenic bacteria
and short chain fatty acids, which support a number of functions and processes that are important to health.
First, acidogenic bacteria
turn biomass into volatile fatty acids and acetic acid.