acid hemolysis test

A test that assesses susceptibility of erythrocytes to hemolysis, which is markedly increased in paroxysmal nocturnal hemoglobinuria (PNH); see there.
Principle In acidified serum, complement is activated by the alternate pathway, binds to RBCs, and lyses PNH cells which are sensitive to complement activation; positive Ham test also occurs in the rare congenital dyserythropoietic anemia type II, also known as HEMPAS
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acid hemolysis test

Ham test
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.