achlorhydria


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achlorhydria

 [a″klor-hi´dre-ah]
absence of hydrochloric acid from gastric juice; associated with pernicious anemia, stomach cancer, and pellagra. adj., adj achlorhy´dric.

a·chlor·hy·dri·a

(ā-klōr-hī'drē-ă),
Absence of hydrochloric acid from the gastric juice.
[G. a- priv. + chlorhydric (acid)]

achlorhydria

/achlor·hy·dria/ (a″klor-hi´dre-ah) absence of hydrochloric acid from gastric secretions.achlorhy´dric

achlorhydria

(ā′klôr-hī′drē-ə)
n.
Absence of hydrochloric acid in the gastric secretions of the stomach.

a·chlor·hy′dric (-drĭk) adj.

achlorhydria

[ā′klôrhī′drē·ə]
Etymology: Gk, a + chloros, not green, hydor, water
an abnormal condition characterized by the absence of hydrochloric acid in gastric secretions. Achlorhydria occurs most commonly in atrophy of the gastric mucosa, gastric carcinoma, and pernicious anemia. It is also found in severe iron deficiency anemia. Malignancy is expected when achlorhydria is seen in combination with peptic ulcers. Protein digestion is severely impaired in patients with achlorhydria, but overall digestion in the digestive tract is relatively normal because trypsin and other enzymes of the pancreas and small intestine are not affected. See also achylia. achlorhydric, adj.

achlorhydria

A condition characterised by an absence of HCl in gastric juice; formally,
(1) a peak acid output in response to a maximally effective stimulus that results in an intragastric pH of > 5.09 in men and > 6.81 in women; or
(2) a maximal acid output of < 6.9 m/mole/h in men and < 5.0 m/mole/h in women; or
(3) a ratio of serum pepsinogen I/pepsinogen II of < 2.9.
 
Associations
Gastric cancer, hip fracture, bacterial overgrowth.

Aetiology
Antiparietal cell antibodies, chronic Helicobacter pylori infection, protein-pump inhibitor therapy.

achlorhydria

Absence of HCl in gastric juice

a·chlor·hy·dri·a

(ā-klōr-hī'drē-ă)
Absence of hydrochloric acid from the gastric juice.
[G. a- priv. + chlorhydric (acid)]

achlorhydria

Absence of the normal hydrochloric acid in the stomach as a result of wasting (atrophy) of the acid-secreting cells in the lining. Achlorhydria is commonly found in PERNICIOUS ANAEMIA when autoimmune damage to the stomach lining is associated with loss of secretion of an intrinsic factor in the stomach that leads to failure of vitamin B12 absorption.

Achlorhydria

An abnormal condition in which hydrochloric acid is absent from the secretions of the gastric glands in the stomach.

a·chlor·hy·dri·a

(ā-klōr-hī'drē-ă)
Absence of hydrochloric acid from the gastric juice.
[G. a- priv. + chlorhydric (acid)]

achlorhydria (ā´klôrhī´drēə),

n the absence of free hydrochloric acid in the stomach, even with histamine stimulation.

achlorhydria

absence of hydrochloric acid from gastric juice.
References in periodicals archive ?
Islet cell tumor of the pancreas with reversible watery diarrhoea and achlorhydria.
Achlorhydria due to proton pump inhibitor use was present in three cases.
In such a scenario, longer duration of achlorhydria, for example lasting six months but not two months, could prolong (or perhaps cause) iron deficiency.
Use of calcium citrate should be recommended for the elderly and those with achlorhydria, as acid is necessary to absorb the less expensive calcium carbonate.
Gastric acidity after pentagastrin stimulation was used either as a continuous variable (pH) or divided into three categories: achlorhydria (0), pH [greater than or equal to] 3 (1), and pH <3 (2).
Achlorhydria Global Clinical Trials Review, Q1, 2011" provides data on the Achlorhydria clinical trial scenario.
Heidelberg testing reveals achlorhydria, frank hypochlorhydria, and hidden hypochlorhydria and allows individualization of dosing.
VIPoma: It is vasoactive intestinal peptide secreting tumors occur as WDHA syndrome: Watery Diarrhoea, Hypokalaemia and Achlorhydria.
Abnormalities of the stomach function may result from achlorhydria which may inhibit the destruction of the ingested microbes.
However, studies to date have failed to show a similar association with omeprazole, a proton pump inhibitor that also produces achlorhydria.
cholerae O1 disease has been associated with autoimmune disease, achlorhydria, and chemotherapy in two of the four previously reported cases (3,6), but our adult patients did not have known longstanding immunosuppression.
Achlorhydria or decreased stomach acid results from atrophy of parietal cells, and there is decreased absorption of vitamin [B.