Also found in: Dictionary, Thesaurus, Financial, Acronyms, Idioms, Encyclopedia, Wikipedia.


1. continuous pain, as opposed to sharp pangs or twinges. An ache can be either dull and constant, as in some types of backache, or throbbing, as in some types of headache and toothache.
2. to suffer such pain.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


A dull, poorly localized pain, usually of less than severe intensity.
Farlex Partner Medical Dictionary © Farlex 2012


A gene on chromosome 7q22 that encodes acetylcholinesterase, which hydrolyses the neurotransmitter acetylcholine at neuromuscular junctions and brain cholinergic synapses, terminating signal transmission. It is also found on red blood cell membranes, where it constitutes the Yt blood group antigen.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Abbreviation for anticholinesterase; acetylcholinesterase.


A dull, generalized or localized pain, usually one of less than severe intensity.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


A persistent dull pain.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005


A dull, poorly localized pain, usually of less than severe intensity.
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about ache

Q. Head aches terrible I am suffering with bad headaches everyday for the past week, so i thought i would check up on it from you guys. When the day nears the noon, my head ache becomes worse. No common cold. Kindly give me a solution.

A. Anyone who suffers from headaches knows they can put a damper on everyday life. But not all headaches are alike. Learn what type of headache you have.

Q. How can i overcome kidney ache? in the morning it appears.after wake up.

A. First of all, it is important to distinguish kidney ache from lower back ache. If you have ever suffered from kidney problems or infections, it might be advisable to see a doctor, and rule out an infection. However, if you are otherwise healthy, and have been experiencing back pain after you wake up, it is very much possible your pain is not from the kidneys, but from the muscles of your back. In this case, some exercise on a daily basis to help strengthen your lower back can very much ease the pain you're experiencing.

Q. how do you help a tooyh ache? cavity

A. Painkillers may relieve the pain but only temporarily, so if you have a tooth pain in my opinion the best way to treat it is consulting a dentist or other doctor.

You may read more here:

More discussions about ache
This content is provided by iMedix and is subject to iMedix Terms. The Questions and Answers are not endorsed or recommended and are made available by patients, not doctors.
References in periodicals archive ?
All groups tested by diazinon in this study revealed an inhibition of AChE activity in all treated organs of C.
AChE activity was detected in the washed fraction and this was due to column overloading.
But I'm lucky my pains aren't debilitating If I didn't work my aches and pains would be worse because I'd be lazy
Carbamtes cause carbamylation of important serine residues on the AChE molecule but in a reversible manner (Colovic et al., 2013; Gupta, 2006).
californica enzyme (TcAChE), one of the jatrorrhizine derivatives was docked to the AChE active site gorge using the Autodock Vina software [20], based on the structure of the complex of TcAChE (PDB entry 5FUM) [21].
AChE is a key enzyme in the cholinergic nervous system, and its levels are consistently decreased in the brain during AD development [12].
Ellman's method was chosen for the enzyme activity assay and it was performed as follows: 400 [micro]l of DTNB, 25 [micro]l of AChE, 375 [micro]l of PBS 74, 100 [micro]l of PBS 7.4 or biperiden, and 100 [micro]l of acetylcholine chloride were pipetted into standard spectrophotometric cuvette.
[48] have made relationship analysis between AChE inhibition and behavior in zebrafish exposed to copper or chlorpyrifos separately or as mixtures.
Sepsis decreased the activity of serum pseudocholinesterase;[sup][6],[7] however, to the best of our knowledge, the changes of AChE activity in the NMJ during sepsis have few directly investigated to date.