acetylcholine receptors

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acetylcholine receptors

proteins which act to bind ACETYLCHOLINE at the cell surface. See CHOLINERGIC.


the acetic acid ester of choline, normally present in many parts of the body and having important physiological functions. It is a neurotransmitter at cholinergic synapses in the central, sympathetic and parasympathetic nervous systems. It is not used clinically but it is the classical cholinergic agonist. Abbreviated ACh.

acetylcholine receptors
structures located at the endorgans, e.g. at the skeletal muscle fibers. The myofibers are stimulated to contract by the interaction of acetylcholine with acetylcholine receptors which are located on the motor end plate or postsynaptic sarcolemma. See also neuromuscular junction.
References in periodicals archive ?
Antagonist of M1 muscarinic acetylcholine receptor prevents neurotoxicity induced by amphetamine via nitric oxide pathway.
Desensitization of nicotinic acetylcholine receptors in central nervous system neurons of the stick insect (Carausius morosus) by imidacloprid and sulfoximine insecticides.
Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models.
1984) Hydrodynamic properties of muscarinic acetylcholine receptors solubilized from rat forebrain.
A final consideration is the potential influence of repeated exposure to suxamethonium, however we are not aware of any direct action of suxamethonium upon acetylcholine receptor regulation.
Functional properties of human skeletal muscle acetylcholine receptors expressed by the TE671 cell line.
These agents have a positively charged quaternary ammonium group that binds to the negatively charged acetylcholine receptor.
Desensitization of mutant acetylcholine receptors in transgenic mice reduces the amplitude of neuromuscular synaptic currents.
Myasthenia gravis is an autoimmune disorder mainly caused by antibodies to the nicotinic acetylcholine receptors (AChR) of the neuromuscular junction [1].
The acetylcholine receptors are divided into muscarinic and nicotinic subtypes.
This damage occurs through mechanisms that include direct interactions with acetylcholine receptors, interference with intracellular signaling cascades, and oxidative stress.