acetylcholine receptor


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Acetylcholine Receptor

A 250-kD nicotinic receptor which undergoes continuous turnover and renewal, a feature that explains the complete recovery of these receptors when damaged by autoimmune antibodies in myasthenia gravis.

acetylcholine receptor

An ion channel that opens when acetylcholine binds to it, so converting chemical diffusion into an electrical signal. Also known as the nicotinic acetylcholine receptor.
References in periodicals archive ?
Alpha 4 beta 2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response.
The muscarinic acetylcholine receptors (mAChR), which are members of the family of receptors that are coupled to guanine nucleotide binding proteins (G proteins) and whose structure is characterized by the seven membrane-spanning [alpha]-helical domains [2, 3], are usually solubilized in digitonin or in a mixture of digitonin and sodium cholate, which have yielded more than 50% of the soluble receptors with retention of ligand binding activity [4, 5].
ACETYLCHOLINE RECEPTOR ANTIBODY (AChRAb) KITS--BINDINGt
Degenerate primers, Bd1, 5'-ATGAARTTYG GNWSNTGGACNTAYGA-3' and Bd2, 5'-GCNACCATRAACATDATRCARTTRAA-3', Were designed based on the conserved motifs of nicotinic acetylcholine receptor family to amplify the cDNA fragments (Gao et al.
Systemic inflammation leads to resistance to atracurium without increasing membrane expression of acetylcholine receptors.
Acetylcholine receptor antibody characteristics in myasthenia gravis.
It is important to understand that the nondepolarizing blocking agents also competitively block acetylcholine receptors at the autonomic ganglia, producing cardiovascular side effects on heart rate and blood pressure.
Nicotine is a naturally occurring alkaloid that is capable of stimulating acetylcholine receptors in both the sympathetic and parasympathetic systems, as well as cholinergic nicotinic receptors at skeletal muscle sites and in the brain.
The antigenic target is the nicotinic acetylcholine receptor (nAChR) of skeletal muscles.
The paper, titled "EVP-6124, a novel and selective a7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of a7 nicotinic acetylcholine receptors," is available online at http://www.
The new image shows a chain of sugar molecules--known to be part of the acetylcholine receptor but previously considered unimportant--located near the receptor's opening.
For example, the patient's blood can be evaluated for the presence acetylcholine receptor antibodies.