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Transport of carnitine and acetylcarnitine by carnitine/organic cation transporter (OCTN) 2 and OCTN3 into epididymal spermatozoa.
1976, In vitro stimulation of himan sperm motility by Acetylcarnitine, Thailand, mahidol university, RamaV1 Road: 85-91.
18) reported marked alterations in the concentrations of lysoPC (18:2) and acetylcarnitine in patients with prediabetes.
Carnitine, acetylcarnitine and the activity of carnitine acyltransferases in seminal plasma and spermatozoa of men, rams and rats.
Effect of carnitine administration on glycine metabolism in patients with isovaleric acidemia: Significance of acetylcarnitine determination to estimate the proper carnitine dose.
The authors go into great detail on smart drugs like deprenyl, acetylcarnitine, hydergine, and SAMe (S-adenosylmethione), and their use as specific treatments for diseases such as Alzheimer's.
Acetylcarnitine was found to have a rapid and enduring antidepressant effect on rats via promoting transcription of the mGlu2 receptor gene in the hippocampus and prefrontal cortex.
Delaying the mitochondrial decay of aging with acetylcarnitine.
We calculated various additional ratios (such as C5 to acetylcarnitine, free carnitine, or various long-chain acylcarnitines), which did not help to further increase the discriminatory power.
Paclitaxel, ethylenediaminetetraacetic acid (EDTA), AF, AAF, phenylmethylsulfonylfluoride (PMSF), leupeptin, Tris, acetylcarnitine, bovine serum albumin (BSA), acetyl coenzyme A (AcCoA), dimethyl sulfoxide (DMSO), dithiothreitol (DTT), and carnitine acetyltransferase were obtained from Sigma Chemical Co.
Using acetyl donors such as acetylcarnitine to increase Krebs cycle carbon flux is one approach.
These mitochondrial abnormalities were reversed by 8 weeks of oral carnitine supplementation, in concert with increased tissue efflux and urinary excretion of acetylcarnitine and improvement of whole body glucose tolerance.