As an example, I recently showed that the metabolite acetylcarnitine
can be quantified by a modified mrs protocol, Which allowed me to demonstrate in humans that acetylcarnitine
concentrations in muscle strongly associate with insulin sensitivity.
Seven were higher in the end-stage OA group compared to no/early stage group (pro-hydroxyproline, acetylcarnitine
, myo-inositol, N-acetylornithine, succinate, glutamine and urea).
The first several chapters cover nutritional medicine from Gaby's perspective, then review a long list of therapeutic agents including individual sections on vitamins, mineral, amino acids, and chemical agents such as acetylcarnitine
to S-Adenosylmethionine (SAMe) that don't fit into those first three categories.
The demonstration of strong positive relationship of free L-carnitine with functional spermatozoal characteristics in this study have further validated the fact that intrasperm L-carnitine is involved in mitochondrial energetics, keeping in mind the various studies which demonstrated carnitine uptake and expression of OCTN2 and OCTN3 carnitine transporters in mouse sperm,13 correlation of intrasperm L-carnitine with motility and survival in cervical mucus of bovine,29 and acetylcarnitine
contributing acetyl groups for energy production in Boar spermatozoa.
Grizard G, Lombard-Vignon N, Boucher D: Changes in carnitine and acetylcarnitine
in human semen during cryopreservation.
1976, In vitro stimulation of himan sperm motility by Acetylcarnitine
, Thailand, mahidol university, RamaV1 Road: 85-91.
concentration and acetylcarnitine
/free carnitine ration was counted according to equations by Schmidt-Sommerfeld  and Seccombe .
and the activity of carnitine acyltransferases in seminal plasma and spermatozoa of men, rams and rats.
Methods used to measure carnitine, acetylcarnitine
Formation during Intense Muscular Contraction in Humans, J Appl Physiol 63, 440-442 (R.
m/z Mean [+ o -] SD Short-chain acylcarnitines Acetylcarnitine
(C2) 260 8.
Effect of carnitine administration on glycine metabolism in patients with isovaleric acidemia: Significance of acetylcarnitine
determination to estimate the proper carnitine dose.