We use aluminum chloride as a contrast agent, which can enhance cellular detail under RCM, similar to a process of acetowhitening
. If we see a positive margin or a positive area, we go back and ablate again with the C[O.sub.2] laser."
The Working Group 1) developed recommended terminology for reporting findings in colposcopy practice in the United States and 2) defined the comprehensive documentation of the procedure as comprising cervix and squamocolumnar junction visibility; acetowhitening
; presence of a lesion; lesion visibility, size and location of lesion(s); vascular changes; other features; and colposcopic impression (TABLE 1).
When sprayed onto Barrett's mucosa, an acetowhitening
reaction occurs such that areas of dysplasia lose their acetowhitening
effect faster than areas without dysplasia.
DSI helps standardize the way colposcopy is performed (with respect to distance, illumination, field of view, and timing), quantifies the acetowhitening
by measuring its intensity and persistence, and has been shown to increase sensitivity [16-18].
MATERIALS AND METHODS The Modified Reid Colposcopic Index (RCI) * Colposcopic Signs Zero Point Colour Low-intensity acetowhitening
(not completely opaque); indistinct acetowhitening
; transparent or translucent acetowhitening
This reaction is called acetowhitening
, and it produces a noticeable effect compared to the normal pinkish color of the surrounding epithelia found in the cervix .
on endocervical polyps, nabothian cysts
Balas, "Wavelet and physical parametric analysis of the acetowhitening
optical effect: comparative evaluation of performances in non-invasive diagnosis of cervical neoplasia," in Proceedings of the 10th International Conference on Information Technology and Applications in Biomedicine: Emerging Technologies for Patient Specific Healthcare (ITAB '10), Corfu, Greece, November 2010.
The aims of this study are to correlate the colposcopic diagnosis to the actual histopathologic diagnosis, and to determine the accuracy, sensitivity and specificity of acetowhitening
in distinguishing premalignant and malignant lesions of the cervix.
may be due to many causes other than dysplastic epithelium.
Acetic acid (3% to 5%) is used to assist the colposcopist in the identification of diseased tissue, which appear characteristically white after the application of the dilute solution of acid (acetowhitening
Many expert colposcopists state that the colposcopic presence of invasive carcinoma in pregnancy is difficult to differentiate from the normal changes of pregnancy,[9,31] even when classic acetowhitening
, vascular patterns, and borders of lesions are considered.