Acetoacetyl-CoA thiolase | definition of acetoacetyl-CoA thiolase by Medical dictionary
acetyl-CoA acetyltransferase (redirected from acetoacetyl-CoA thiolase)
an acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis.
thiolase An obsolete generic term for any enzyme (e.g., acetyl CoA acetyltransferase [EC 18.104.22.168]) which catalyses a reaction between a compound, R–R’, and a thiol, R’–SH, forming R–S–R’ and R'–H.
a·ce·tyl-CoA a·ce·tyl·trans·fer·ase (as'ĕ-til as'e-til-trans'fĕr-ās)
References in periodicals archive
Activation of liver carnitine palmitoyltransferase-1 and mitochondrial acetoacetyl-CoA thiolase is associated with elevated ketone body levels in the elasmobranch Squalus acanthias.
Purification, kinetic mechanism and regulation of different forms of mitochondrial acetoacetyl-CoA thiolases from ox liver.