acetyl-CoA acetyltransferase

(redirected from acetoacetyl-CoA thiolase)

a·ce·tyl-CoA a·ce·tyl·trans·fer·ase

an acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis.

thiolase

An obsolete generic term for any enzyme (e.g., acetyl CoA acetyltransferase [EC 2.3.1.9]) which catalyses a reaction between a compound, R–R’, and a thiol, R’–SH, forming R–S–R’ and R'–H.

a·ce·tyl-CoA a·ce·tyl·trans·fer·ase

(as'ĕ-til as'e-til-trans'fĕr-ās)
An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis.
Synonym(s): acetoacetyl-CoA thiolase, acetyl-CoA thiolase.
References in periodicals archive ?
Activation of liver carnitine palmitoyltransferase-1 and mitochondrial acetoacetyl-CoA thiolase is associated with elevated ketone body levels in the elasmobranch Squalus acanthias.
The second genetic disorder included in this study is an organic acid disorder called Mitochondrial acetoacetyl-CoA thiolase (T2), commonly known as Beta-ketothiolase deficiency.
Activities of 3-hydroxybutyrate dehydrogenase, 3-oxoacid CoA-transferase and acetoacetyl-CoA thiolase in relation to ketone-body utilisation in muscles from vertebrates and invertebrates.
35) The MVA pathway begins with the synthesis of acetoacetyl-CoA, which was first reported to be biosynthesized via a thioester-dependent Claisen condensation reaction between two molecules of acetyl-CoA, and is catalyzed by acetoacetyl-CoA thiolase (EC 2.