ACE

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angiotensin

 (ACE) [an″je-o-ten´sin]
a vasoconstrictive substance formed in the blood when renin is released from the juxtaglomerular apparatus in the kidney. The enzymatic action of renin acts on angiotensinogen to form the decapeptide angiotensin I, which is relatively inactive. It in turn is acted upon by peptidases (converting enzymes), chiefly in the lungs, to form the octapeptide angiotensin II, a powerful vasopressor and a stimulator of aldosterone secretion by the adrenal cortex. By its vasopressor action, it raises blood pressure and diminishes fluid loss in the kidney by restricting blood flow. Angiotensin II is hydrolyzed in various tissues to form heptapeptide angiotensin III, which has less vasopressor activity but more effect on the adrenal cortex.
angiotensin-converting enzyme (ACE) an enzyme of the hydrolase class that catalyzes cleavage of a dipeptide from the C-terminal end of angiotensin I to form activated angiotensin II; called also peptidyl-dipeptidase A.
angiotensin-converting enzyme inhibitors competitive inhibitors of angiotensin-converting enzyme, which converts angiotensin I to angiotensin II and inactivates bradykinin. ACE inhibitors, such as captopril, are antagonists of the renin-angiotensin-aldosterone system and potentiators of the kinin system and are used for treatment of hypertension, usually in conjunction with a diuretic. They are also used as vasodilators in the treatment of congestive heart failure.

ACE

ACE

(1) Abciximab & Carbostent Evaluation in Acute Myocardial Infarction. A trial comparing outcomes of carbon-coated stenting of an infarct-related artery with and without abciximab.
Primary endpoint 30-day MACE (major acute coronary events)
Conclusion Abciximab + IRA stenting may be a viable reperfusion strategy in patients with acute myocardial infarction undergoing primary percutaneous revascularization.
(2) ASA & Carotid Endarterectomy. A trial comparing high- and low-dose aspirin to reduce the risk of stroke in patients undergoing carotid endarterectomy.
Primary endpoints 30-day MACE (major acute coronary events), stroke
Conclusion Low-dose (80, 325 mg) ASA patients did better

ACE

Angiotensin-converting enzyme, see there. Cf ACE inhibitors, also
1. Acute Care for Elderly.
2. Adriamycin, cyclophosphamide, etoposide.
3. Alcohol, chloroform, ether–obsolete anesthetic cocktail.
4. American College of Epidemiology.

ACE

Abbreviation for angiotensin-converting enzyme.

ACE

See ANGIOTENSIN-CONVERTING ENZYME.
References in periodicals archive ?
Reports over the weekend claimed that Saddam's former top official Mahmud al-Tikriti - the Ace of Diamonds in the US deck of cards of most wanted Iraqis - told interrogators that he had spent time hiding with the trio in Iraq after the war ended.
A distant cousin of Saddam,Mahmud is also the ace of diamonds on the US deck of cards portraying leaders of Saddam's regime.
The other son Uday is Ace of Diamonds and Chemical Ali - Ali Hassan Majeed, thought to have died in Basra - is the Ace of Hearts.
At that point the only hand he could have that I wouldn't be a huge favourite against was Ace of diamonds, King of diamonds, but I thought it was probably more likely that he was trap-checking with Ace Ace King King, as I would have expected him to do a continuation bet on that sort of flop even if he missed it.
Four clubs from South shows the ace of clubs, Four diamonds by North the ace of diamonds and four hearts by South the ace of hearts.
Now Telewest will instead send out the ace of diamonds, which is linked with good luck.
The turn is the Ace of diamonds and the river is the Jack of diamonds giving Sean a royal flush.
Your losing clubs will go on the diamonds but the ace of diamonds is your third loser so how will you tackle trumps?
Eddie goes all-in for his last 700 and shows the Ace of diamonds and the 7 of hearts.
South crossed to the ace of diamonds, ruffed another club and then led a diamond.
But the river is Ace of diamonds, doubling Marty up.