accelerated phase

accelerated phase

A nonspecific term that can refer to virtually any disease characterised by a burst of cell growth or activity after a period of relative indolence.

accelerated phase

Oncology A progressive phase of CML characterized by immature, defective WBCs in BM and peripheral blood which is higher in the chronic phase, but less than in the blast phase. See Blast crisis.
References in periodicals archive ?
Treatment of adult patients with T315I-positive chronic myeloid leukemia (chronic phase, accelerated phase, or blast phase) or T315I-positive Philadelphia chromosome positive acutelymphoblastic leukemia (Ph+ ALL).
Romeo, logistics officer, leads 14 divisions during an accelerated phase of base expansion in support of Marine Air Group 12 and the relocation of Carrier Air Wing 5.
Professor Mark Drakeford said: "I'm pleased to announce we will be making this medicine available to adult patients with chronic phase, accelerated phase or blast phase chronic myeloid leukaemia, following a recommendation from the All Wales Medicines Strategy Group.
prospect of now moving into an accelerated phase of our exploration
to treat Philadelphia chromosome-positive chronic myeloid leukemia (CML) blastic phase, accelerated phase or patients in chronic phase after a-interferon failure.
When he presented to the hospital clue to an accelerated phase of CML, it was learned that he had discontinued imatinib therapy for the last 8 months.
Of the 4 cases (2 accelerated phase and 2 blast phase) they reported with transformed disease, 2 of the cases with excess blasts (accelerated phase) had increased megakaryocytes.
The current iPad was launched just months after its predecessor, and the iPhone is believed to be about to enter a similarly accelerated phase of development.
Indian real estate is poised to enter an accelerated phase of growth in wake of international investors, the likes of US-based Warburg Pincus, Blackstone Group, Broadstreet, Morgan Stanley Real Estate Fund (MSREF), Columbia Endowment Fund, California Public Employees' Retirement System (CalPERS), Hines, Tishman Speyer, Sam Zell's Equity International, JP Morgan Partners and Amaranth Advisors, exploring investment opportunities in India.
The study included 40 patients in the chronic phase, 16 in the accelerated phase, and 10 in the blast phase.
Patients in the study will be enrolled in one of four cohorts: patients with accelerated phase CML, patients with blast phase CML, patients with chronic phase CML and patients with Philadelphia chromosome-positive ALL with the T315I mutation.

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