Coccygeal polypoid eccrine nevus is a benign unique eccrine nevus located in the coccygeal area, characterized histopathologically by normal or hyperplastic eccrine glands surrounded by normal fibroadipose tissue with occasional overlying acanthotic
and hyperkeratotic epidermis.
At 10x magnification a regularly acanthotic
epidermis with hyperkeratosis alternating with parakeratosis.
The epithelium is acanthotic
and shows basal atypia.
The histopathology from a papule showed hyperkeratotic and acanthotic
and hyper-keratotic stratified squamous epithelium is also present with elongated rete ridges.
epithelium and corium is seen corresponding to surrounding outline.
The histopathology of BD lesions is characterized by hyperkeratosis; parakeratosis; loss of orderly maturation, polarity, and a granular layer; and keratinocytic atypia involving the entire acanthotic
A shave biopsy of a neck plaque identified a hyperkeratotic, acanthotic
, spongiotic dermatitis with lymphocytes and scattered eosinophils.
In group 2, the feather follicles at the 20-second treated site (primary feather 10) had acanthotic
epithelium and mild heterophilic or lymphocytic inflammation (Fig 3).
Other Digital Fibromas Including Acral and Subungual Angiofibroma, Acquired Digital Fibrokeratoma, and Acquired Reactive Digital Fibroma.--Acquired digital fibrokeratoma (ADF) is normally a polypoid acral lesion histologically showing vertically oriented collagen and fibrocytes in the dermis, which are typically encased by the acanthotic
, hyperkeratotic epidermis.
However, a deep-seated nodule was found in the umbilicus with the clinical impression of "umbilical sinus." He underwent surgery and excisional biopsy; histopathologic examination revealed a polypoid lesion protruded to umbilicus covered by acanthotic
epidermis (Figure 2) with a prominent increase in eccrine coils and dermal fibrosis (Figure 3).
2 of the cases of Bullous pemphigoid (BP) had hyperkeratotic and acanthotic
epidermis and all cases showed spongiosis with basal cell vacuolation.