acanthosis

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acanthosis

 [ak″an-tho´sis]
diffuse hypertrophy or thickening of the prickle cell layer of the skin. adj., adj acanthot´ic.
acanthosis ni´gricans diffuse acanthosis with gray, brown, or black pigmentation, chiefly in the axillae and other body folds, occurring in an adult form, often associated with an internal carcinoma (called malignant acanthosis nigricans) and in a benign, nevoid form, more or less generalized. A benign form associated with obesity, which is sometimes due to endocrine disturbance, is called pseudo-acanthosis nigricans. (See Atlas 2, Part E).

ac·an·tho·sis

(ak-an-thō'sis),
An increase in the thickness of the stratum spinosum of the epidermis.
[G. fr. acantho-, thorn + G. -osis, condition]

acanthosis

Hyperplasia of the squamous epithelium of mucocutaneous surfaces.
Diseases with
Psoriasis, granulomatous reactions, lymphocytic infiltrates.

Mechanism
Defective epidermal cell kinetics.

ac·an·tho·sis

(ak-an-thō'sis)
An increase in the thickness of the stratum spinosum of the epidermis.
[G. fr. acantho-, thorn + G. -osis, condition]

acanthosis

A disease process in the skin featuring overgrowth and thickening of the prickle-cell layer of the EPIDERMIS. This layer lies above its parent layer, the BASAL cell layer, and local overgrowth results in raised, roughened areas such as warts or the lesions of PSORIASIS or ECZEMA.

ac·an·tho·sis

(ak-an-thō'sis)
Increased thickness of epidermal stratum spinosum.
[G. fr. acantho-, thorn + G. -osis, condition]