Acanthamoeba

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Acanthamoeba

 [ah-kan″thah-me´bah]
a genus of free-living ameboid protozoa found usually in fresh water or moist soil. Certain species, such as A. castella´ni, A. poly´phaga, A. astronyx´is, and A. culbert´soni, may occur as opportunistic human pathogens, causing an acute fatal or chronic infection of the eye, brain, liver, kidney, lung, pancreas, and skin in patients with underlying disease or in immunocompromised patients.

Acanthamoeba

(ă-kan'thă-mē'bă),
A genus of free-living ameba (family Acanthamoebidae, order Amoebida) found in and characterized by the presence of acanthopodia. Human infection includes invasion of skin or colonization following injury, corneal invasion and colonization, and possibly lung or genitourinary tract colonization; a few cases of brain or central nervous system invasion have occurred, but not solely by the olfactory epithelium route of entry as with the more virulent infections caused by Naegleria fowleri. Species responsible are chiefly Acanthamoeba culbertsoni, but cases have been reported involving Acanthamoeba castellanii, Acanthamoeba polyphaga, and Acanthamoeba astronyxis. Most cases have been chronic rather than fulminating and rapidly fatal as with N. fowleri infection.
[G. akantha, thorn, spine, + Mod. L. amoeba, fr. G. amoibē, change]

Acanthamoeba

A genus of free-living pathogenic amoebae, which are ubiquitous in the environment, the cycle of which consists of 2 stages: a trophozoite (which is 14–40 µm in diameter) and a cyst (which has a double-layered wall with a diameter of 12–16 µm).

Sources
Tap water, dust, soil, sewage, air-conditioning units.
 
Diseases caused by:
Amoebic keratitis, acanthamoeba granulomatous encephalitis.

Acanthamoeba

A genus of free-living pathogenic amoebas Sources tap water, dust, soil, sewage, air conditioning units. See Acanthamebiasis. Cf Leptomyxid, Naegleria.
References in periodicals archive ?
In 18 years in practice, I'd never seen Acanthamoebae in the wild: until now, that is.
Improved axenization method reveals complexity of symbiotic associations between bacteria and acanthamoebae. Environ Microbiol Rep.
Nevertheless, trophozoites produced some focal injury on the cells by means of phagocytic structures of diverse size through which they engulfed portions of cells, a behavior that was previously observed in other Acanthamoebae such as A.
Acanthamoebae have been well recognized as opportunistic pathogens causing fatal GAE in patients with tuberculosis and AIDS and following organ transplants since the 1990s.
The acanthamoebae were collected by washing the plates with saline and a standard inoculum of 1 x [10.sup.3] cells/ ml was prepared and used for all the subsequent experiments.
Use of subgenic 18S ribosomal DNA PCR and sequencing for genus and genotype identification of acanthamoebae from humans with keratitis and from sewage sludge.
(12) Several reports describe infection of Acanthamoebae with environmental (13) or pathogenic mycobacteria such as M.
Worryingly it also may well be that the disinfecting solutions we rely upon are not as effective as we think particularly against some strains of Pseudomonas which Acanthamoebae feed upon.
Multiplex real-time PCR assay for simultaneous detection of Acanthamoebae spp., Balamuthia mandrillaris, and Naegleria fowleri.
A small number (3/25) of clones showed closest similarity to acanthamoebae belonging to the T4 clade, which includes strains considered to be human pathogens, including some A.
Waddlia chondrophila was isolated from the brain and nervous tissue of an aborted bovine fetus in Germany (2), and Parachlamydia acanthamoebae and other unidentifi ed Chlamydia-like species were identified in 18.3% of bovine placenta samples in Switzerland (3,4).
Parachlamydia acanthamoebae and Protochlamydia naegleriophila belong to the family Parachlamydiaceae (1,4).