acanthamoeba infection

Acanthamebiasis

An infection by Acanthamoeba spp, which is characterised by pustules, vasculitis, granulomatous amoebic encephalitis, and granulomas of skin. It is common in immunocompromised or immunosuppressed individuals, and may lead to death.
High-risk AIDS, alcohol abuse, diabetes, immunosuppression-transplantation-related, cancer—leukaemia, lymphoma—malnutrition
Management Chlorhexidine, propamidine, miconazole nitrate

acanthamoeba infection

Infection, with various species of the genus Acanthamoeba . Acanthamoeba culbertsoni is a ubiquitous soil AMOEBA that may cause infection in people who have suffered facial injuries or who have DIABETES or LYMPHOMAS. Abscess-like masses occur in the skin, lungs, middle ear and even the brain. Infection of the CORNEA can also occur in contact lens wearers, usually from Acanthamoeba polyphaga . Acanthamoeba cysts are impervious to chlorine in concentrations up to 50 parts per million. They may therefore survive in domestic water supplies. Treatment is with AMPHOTERICIN-B.
References in periodicals archive ?
A positive culture of the case may suggest Acanthamoeba infection, but does not confirm Acanthamoeba infection.
Disseminated acanthamoeba infection is a rare disease characterized by widespread granulomatous infiltration of the skin and extracerebral organs; it usually occurs in immunocompromised patients.
However, a negative culture does not necessarily rule out Acanthamoeba infection. Confocal microscopy and polymerase chain reaction assays to detect Acanthamoeba can also assist with diagnosis.
Early diagnosis of Acanthamoeba infection during routine cytological examination of cerebrospinal fluid.
[26] discussed the relation between Acanthamoeba infection and S.epidermidis&S.aureus.
To treat the Acanthamoeba infection, the patient was started on oral itraconazole and intravenous metronidazole; IV pentamidine was added 2 days later.
They conclude that Acanthamoeba infection rates appear to be closely related to improper maintenance and cleaning of soft lenses by users.
Disseminated Acanthamoeba infection in a renal transplant recipient.
Evidence of Acanthamoeba infection was recently found by PCR in brain tissue of a patient with lupus, even without isolating the ameba (8).
In conclusion, Acanthamoeba infection was demonstrated by hematoxylin and eosin and immunostaining of brain tissue and PCR detection of ameba mitochondrial DNA in brain tissue.
The increasing importance of Acanthamoeba infections. J Eukaryot Microbiol, 2000; 47: 29-36.
Among their topics are high-throughput screenings: new breeze in anti-Trypanosoma cruzi drug discovery, protein glycosylation in Trypanosoma cruzi and strategies based on mass spectrometry for characterizing glycans and glycoproteins, omics approaches for understanding gene expression in Leishmania: clues for tackling Leishmaniasis, Entamoeba histolytica: from high-throughput technology to new drugs, and gene silencing and therapeutic targets against Acanthamoeba infections. Distributed in the US by Ingram Content Group.