Infection by free-living soil and water amebae of the genus Acanthamoeba that may result in necrotizing dermal lesions, fulminating and usually fatal primary amebic meningoencephalitis, or subacute or chronic granulomatous amebic encephalitis.
AcanthamebiasisAn infection by Acanthamoeba spp, which is characterised by pustules, vasculitis, granulomatous amoebic encephalitis, and granulomas of skin. It is common in immunocompromised or immunosuppressed individuals, and may lead to death.
High-risk AIDS, alcohol abuse, diabetes, immunosuppression-transplantation-related, cancer—leukaemia, lymphoma—malnutrition
Management Chlorhexidine, propamidine, miconazole nitrate
acanthamebiasisAcanthamoeba infection Infectious disease An infection by Acanthamoeba spp, characterized by pustules, vasculitis, granulomatous amebic encephalitis, and granulomas of skin; it is common in weak or immunocompromised subjects, often leading to death High-risk groups AIDS, alcohol abuse, DM, immunosuppression-transplantation-related, cancer–leukemia, lymphoma, malnutrition Treatment Uncertain; a case of A rhysodes responded to topical chlorhexidine and ketoconazole, systemic pentamidine–IV and oral itraconazole
Infection by free-living soil amebae of the genus Acanthamoeba that may result in a necrotizing dermal or tissue invasion, or a fulminating and usually fatal primary amebic meningoencephalitis.