absorbed dose


Also found in: Dictionary, Thesaurus, Legal, Acronyms, Encyclopedia, Wikipedia.
Related to absorbed dose: Equivalent dose

dose

 [dōs]
the quantity to be administered at one time, as a specified amount of medication or a given quantity of radiation.
absorbed dose that amount of energy from ionizing radiations absorbed per unit mass of matter, expressed in rads.
air dose the intensity of an x-ray or gamma-ray beam in air, expressed in roentgens.
booster dose an amount of immunogen (vaccine, toxoid, or other antigen preparation), usually smaller than the original amount, injected at an appropriate interval after primary immunization to sustain the immune response to that immunogen.
curative dose (CD) a dose that is sufficient to restore normal health. See also median curative dose.
divided dose fractionated dose.
effective dose (ED) that quantity of a drug that will produce the effects for which it is administered. See also median effective dose.
erythema dose that amount of radiation that, when applied to the skin, causes erythema (temporary reddening).
fatal dose lethal dose.
fractionated dose a fraction of the total dose prescribed, as of chemotherapy or radiation therapy, to be given at intervals, usually during a 24-hour period.
infective dose (ID) that amount of a pathogenic agent that will cause infection in susceptible subjects. See also median infective dose and tissue culture infective dose.
lethal dose (LD) that quantity of an agent that will or may be sufficient to cause death. See also median lethal dose and minimum lethal dose.
loading dose a dose of medication, often larger than subsequent doses, administered for the purpose of establishing a therapeutic level of the medication.
maintenance dose the amount of a medication administered to maintain a desired level of the medication in the blood.
maximum tolerated dose tolerance dose.
maximum permissible dose the largest amount of ionizing radiation that one may safely receive within a specified period according to recommended limits in current radiation protection guides. The specific amounts vary with age and circumstance.
median curative dose (CD50) a dose that abolishes symptoms in 50 per cent of test subjects.
median effective dose (ED50) a dose that produces the desired effect in 50 per cent of a population.
median infective dose (ID50) that amount of pathogenic microorganisms that will produce demonstrable infection in 50 per cent of the test subjects.
median lethal dose (LD50) the quantity of an agent that will kill 50 per cent of the test subjects; in radiology, the amount of radiation that will kill, within a specified period, 50 per cent of individuals in a large group or population.
median tissue culture infective dose (TCID50) that amount of a pathogenic agent that will produce infection in 50 per cent of cell cultures inoculated.
minimum lethal dose
1. the amount of toxin that will just kill an experimental animal.
2. the smallest quantity of diphtheria toxin that will kill a guinea pig of 250-gm weight in 4 to 5 days when injected subcutaneously.
reference dose an estimate of the daily exposure to a substance for humans that is assumed to be without appreciable risk; it is calculated using the no observed adverse effect level and is more conservative than the older margin of safety.
skin dose (SD)
1. the air dose of radiation at the skin surface, comprising the primary radiation plus backscatter.
2. the absorbed dose in the skin.
threshold dose the minimum dose of ionizing radiation, a chemical, or a drug that will produce a detectable degree of any given effect.
threshold erythema dose (TED) the single skin dose that will produce, in 80 per cent of those tested, a faint but definite erythema within 30 days, and in the other 20 per cent, no visible reaction.
tissue culture infective dose (TCID) that amount of a pathogenic agent that will produce infection when inoculated on tissue cultures; used with a numeric qualifier.
tolerance dose the largest quantity of an agent that may be administered without harm. Called also maximum tolerated dose.

ab·sorbed dose

the amount of energy absorbed per unit mass of irradiated material at the target site; in radiation therapy, the former unit for absorbed dose is the rad (100 ergs/g); the current (SI) unit is the gray (1 J/kg or 100 rad).

absorbed dose

the energy imparted by ionizing radiation per unit mass of irradiated material at the place of interest. The SI unit of absorbed dose is the gray, which is 1 J/kg and equals 100 rad.

Absorbed Dose

The energy conveyed or imparted by ionising radiation per unit mass of irradiated material—e.g., tissue—defined as an International System (SI) unit, the gray (Gy), which corresponds to 100 rads, the now-retired unit for an absorbed dose.

absorbed dose

Radiation physics The energy imparted by ionizing radiation per unit mass of irradiated material–eg, tissue, defined as an SI unit, the gray–Gy, which corresponds to the 100 rads, the old unit for absorbed dose

ab·sorb·ed dose

(ăb-sōrbd' dōs)
1. The amount of a substance that is absorbed by the body by penetrating an epithelial barrier such as the skin, eyes, respiratory tract, or gastrointestinal tract.
2. The amount of energy absorbed per unit mass of irradiated material at the target site.
3. radiation therapy The former unit for absorbed dose is the rad; the current (SI) unit is the gray.

ab·sorbed dose

(ab-sōrbd' dōs)
Amount of energy absorbed per unit mass of irradiated material at the target site; in radiation therapy, the former unit for absorbed dose is the rad (100 ergs/g); the current (SI) unit is the gray (1 J/kg or 100 rad).

dose

the quantity to be administered at one time, as a specified amount of medication or a given quantity of radiation.

absorbed dose
that amount of energy from ionizing radiations absorbed per unit mass of matter, expressed in Grays.
air dose
the intensity of an x- or gamma-ray beam in air, expressed in coulombs per kilogram.
booster dose
an amount of immunogen (vaccine, toxoid or other antigen preparation), sometimes smaller than the original amount, injected at an appropriate interval after primary immunization to enhance and sustain the immune response to that immunogen.
curative dose (CD)
a dose that is sufficient to restore normal health.
divided dose
a fraction of the total quantity of a drug prescribed to be given at intervals, usually during a 24-hour period.
dose equivalent limits
the limits of ionizing radiation set for radiation workers and the general public by the International Commission on Radiological Protection. For radiology workers this limit for the whole body is 50 mSv.
fatal dose
lethal dose.
dose fractions
in radiation therapy, the small doses given to reach the total radiation dose during the treatment period.
infectious dose 50 (ID50)
that amount of pathogenic microorganisms that will produce infection in 50% of the test subjects.
infective dose (ID)
that amount of pathogenic microorganisms that will cause infection in susceptible subjects.
lethal dose (LD)
the amount of toxin or drug that will kill an animal.
dose level
the amount administered per unit of body weight.
loading dose
the initial large dose of a drug given to bring tissue and fluid levels to an effective concentration quickly. Called also priming dose.
maintenance dose
the smaller doses given to maintain effective levels in body fluids and tissues after the loading dose has achieved the concentration desired.
maximum permissible dose
see dose equivalent limits (above).
median curative dose (CD50)
a dose that abolishes signs in 50% of test animals.
median effective dose (MED)
the dose that produces the desired effect in 50% of the test animals.
median lethal dose (MD50)
the quantity of an agent that will kill 50% of the test subjects; in radiology, the amount of radiation that will kill, within a specified period, 50% of individuals in a large group or population.
minimum lethal dose (MLD)
the lowest dose which kills all of the test subjects.
dose rate
the amount administered per unit of time.
dose response
1. the incremental change in the subject per unit of additional dose. The response as a function of the dose.
2. the frequency of occurrence of a disease as the intake of the suspected risk factor increases. The relationship is expressed by the proximity of the illustrative curve to the expected relationship.
skin dose
1. the air dose of radiation at the skin surface, comprising the primary radiation plus backscatter.
2. the absorbed dose in the skin.
tolerance dose
the largest quantity of an agent that may be administered without harm.
References in periodicals archive ?
At an absorbed dose of 300 kGy about 25 radicals are generated on the high molecular mass PP.
14 Present work Table 5: levels in the air absorbed dose rate (D) obtained in our study and other global values and comparing them with values of other international studies in other countries.
The mechanistic nature of the PBPK model, including the process of linking exposure measurements of a toxic chemical to urinary biomarker data and ultimately to the absorbed dose estimation, makes its application favorable in risk assessment.
Figure 3 shows the stress-strain relationship in tension for the pure PE and PE + 10 PLC blend previously irradiated up to the absorbed dose of 150 kGy at the temperature of 145 [degrees] C.
2]), is used in the calorimeter, the temperature rise, after a small priming dose, will correspond exactly to the energy deposited by the absorbed dose and the heat defect will equal zero [1].
c] at an absorbed dose four times smaller than that for SEVA-113-12, which does [TABULAR DATA FOR TABLE 3 OMITTED] not contain this additive.
The SI unit of absorbed dose is the gray; 1 Gy = 1 J/kg.
However, regardless of the exposure route, the absorbed dose is mostly metabolized, and the TCPy metabolite is distributed throughout the body in the blood and eliminated through the kidney (Figure 2).
He concluded that the ZEVALIN biodistribution and estimated radiation absorbed dose to normal body organs were not affected by prior treatment with Rituxan given two to 23 months earlier.
where D is the maternal intake dose of MeHg (micrograms per kilogram per day), C is the measured Hg concentration in cord blood (for this analysis, the cord blood concentration is assumed to be the BMD (benchmark dose) value of 58 [micro]g/L identified by the NRC (2000), R is the ratio of cord blood Hg concentration/ maternal blood Hg concentration (unitless), b is the rate constant for elimination of MeHg from the blood (per day), V is the maternal blood volume (liters), W is the maternal body weight (kilograms), A is the fraction of the ingested dose that is absorbed (unitless), and F is the fraction of the absorbed dose that is present in the blood at steady state (unitless).
We analyzed the urine samples for 3,5,6-trichloropyridinol, the primary urinary metabolite of chlorpyrifos, and used the results to estimate the children's absorbed dose.