absolute risk


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absolute risk

Probability that a specified event will occur in a specified population, in contrast to the relative risk of the event.

Absolute Risk

The observed or calculated probability of the occurrence of an event, X—e.g., toxic exposure, infection, etc.—in a population relative to its exposure to a specific hazard or pathogen. Absolute risk is risk stated without any context whatsoever.
Example 172,570 people in America were diagnosed with lung cancer in 2005, a year in which there were approximately 290,000,000 Americans, yielding an absolute risk of 1:1,680 of being diagnosed with lung cancer. Adding context—e.g., age, smoking history, industrial exposure, etc.—is used to define a person’s relative risk of suffering a particular condition.

absolute risk

Epidemiology The observed or calculated probability of occurrence of an event, X, in a population related to exposure to a specific hazard, infection, trauma; the number of persons suffering from a disease when the exposed population is known with certainty. Cf Relative risk.
References in periodicals archive ?
"These results confirm anecdotal reports that sexual activity can trigger a heart attack, but more importantly they demonstrate that the absolute risk is very low," Muller says.
"If you look at that study, between the placebo and Chantix, the absolute risk is barely a quarter of a percentage more with Chantix," says lyaad Hasan, CNP, of Cleveland Clinic's Taussig Tobacco Cessation Program.
The absolute risk reduction was 3.33%, and the NNT was 300 women for I year.
This corresponded to an absolute risk for any GI cancer of 101 per 100,000 person-years in the group with villous atrophy, wrote the authors, or an excess risk over the nonceliac population of 2 per 100,000.
Despite this finding, the researchers concluded that the absolute risk of suffering a cardiovascular event is minimal, and the long-term benefits for vascular health that dental treatments confer probably outweigh any short-term risks.
They found that women over the age of 60 with CCS Class IV angina (as defined by the Canadian Cardiovascular Society) faced a 21 percent higher absolute risk of developing CAD than men.
The last decade also has produced numerous studies evaluating the reproductive safety of selective serotonin reuptake inhibitors (SSRIs) with respect to the risk for major malformations, with most data supporting safety or suggesting a small absolute risk of malformations.
Nevertheless, it confirmed the greater risk of VTE with OC use in thrombophilic women, and clarified the absolute risk of VTE over a woman's reproductive life, which remains fairly stable because women with thrombophilic deficiencies are at such high risk to begin with.
The 10-year absolute risk for CHD was nearly 22% for high-risk patients and 9% for the low-risk patients.
The study said: "The absolute risk of unexplained stillbirth at or after 39 weeks' gestation was 1.1 per 1,000 women who had had a previous Caesarean and 0.5 per 1,000 in those who had not."
The researchers found that with increasing psychological distress level, there was an increase in absolute risk of MI and stroke.
This corresponded to an absolute risk for any GI cancer of 101/100,000 person - years in the group with villous atrophy, wrote the authors, or an excess risk over the nonceliac population of 2/ 100,000.