This lower rate which is partly attributed to superior adjuvant systemic therapy in modern trails reduces the absolute benefit
in the intermediate group which is the critical component guiding treatment decisions.
"Because of these factors, the absolute benefit
that results from any proportionally lower rate of cardiovascular disease may be less than the benefit observed in studies from previous decades and is less likely than it had been to outweigh the risk of adverse events from aspirin," investigators said in their report.
Oncologists typically recommend adjuvant chemotherapy for the half of all breast cancers that are hormone receptor positive, HER2 negative, and node negative, even though its absolute benefit
in reducing recurrences in this population is small.
TAILORx participants with Breast Recurrence Score results from 26 to 100 were treated with chemotherapy plus endocrine therapy based on the prior results from the NSABP B-20 study, which showed an absolute benefit
of chemotherapy greater than 20%.
'The absolute benefit
level per household also differs significantly across country income groups.
(1) At the 25-week follow-up (after the MA patients had been off the therapy for 13 weeks), a statistically, but not clinically, significant difference was observed in the number of MA patients who gained [greater than or equal to] 1.82 kg (absolute benefit
increase=40.2%; 95% CI, 13.4%-66.9%; number needed to treat [NNT]=2; 95% CI, 1-8).
Absolute risk of the patient and amount of LDL-C reduction can be used to predict the absolute benefit
of therapy and the cost effectiveness of therapy, he added.
The higher the estimated risk, the greater the absolute benefit
. If your estimated likelihood of having a heart attack or stroke over 10 years exceeds 7.5-10 percent, statin therapy should be considered and discussed with your physician.
Her brilliant campaigning has been to the absolute benefit
of disabled people in her Yorkshire community, and disabled people across Britain."
 Randomised trials published in the past year have shown significant benefit of mechanical thrombectomy within 6 hours of onset over best medical treatment in patients with acute ischaemic stroke due to proximal large-vessel occlusion (terminal internal carotid, middle cerebral and anterior cerebral arteries), with an absolute benefit
(modified Rankin score 0-2 at 90 days) for functional outcome ranging from 13.5% to 31% for thrombectomy over best medical treatment.
The fact is that cheaper oil is an absolute benefit
to humanity but unfortunately, investors are falling for warnings from scaremongering pundits, who speak from a purely academic perspective, and are negatively reacting to what should be good news.
In the first group, we present the absolute benefit