abrin


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ab·rin

(ab'rin),
A phytotoxin from jequirity seeds or Indian glycyrrhiza, the red seeds (Abrus precatorius); used in ophthalmology.

abrin

(ā′brĭn)
n.
A poisonous protein found in the seeds of the rosary pea.

abrin

A phytotoxin in the seeds of Abrus precatorius, the jequerity or rosary pea, which is similar to ricin; poisoning can occur by inhalation, ingestion or absorption.

Clinical findings
Internal bleeding, GI complaints, mucosal irritation.

Mechanism
Inhibits protein synthesis; once used for chronic eye disorders, it is being evaluated as a potential chemotherapeutic.

abrin

An anticancer drug derived from the jequirity bean Abrus precatorius . Abrin contains toxic LECTINS that are more effective in inhibiting protein synthesis in some cancers than in normal cells.
References in periodicals archive ?
A toxin so potent as abrin can be expected to have appeal as a murder weapon as well as a chemical warfare agent.
Different plant parts of this species contain various kinds of alkaloids such as glycerrhizin, precol, abrol, abrasine, abrins (A and B) which impart its medicinal value (Joshi, S.G., 2000; Ghani, A., 2003).
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells.
* Bruce Hammock and Ian Kennedy, University of California, Davis, to work on the development of miniaturized sensors for use in detecting botulinum toxin, ricin, and abrin
The herbal poison abrin, extracted from precatory beans, is very similar to ricin.
Phytotoxin--A poisonous substance of plant origin; e.g., abrin from rosary pea, Abrus precatorius; ricin from castor bean, Ricinus communis; crotin from croton, Codiaeum variegatum; and robin from black locust, Robinia pseudoacacia.
The focus of phase I of this research contract will be on the development of biosensors for Abrin and Ebola.
Computer analysis showed that Ali, from Prescot Road, Old Swan, first began trawling the internet for information on poisons such as abrin, ricin and cyanide in October last year.
The computer showed that Ali had begun searching Google in October last year for poisons such as abrin, ricin and cyanide.
Type II RIP family is widely represented in plants of different taxonomic origins such as ricin, viscumin, abrin, volkesin, etc.