abdominoperineal resection


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abdominoperineal resection (APR),

a surgical cancer treatment involving resection of the lower sigmoid colon, rectum, anus, and surrounding skin and formation of a sigmoid colostomy; performed as a synchronous or sequential transabdominal and perineal procedure.

abdominoperineal resection

The surgical excision of the lower rectum and anus, resulting in the loss of the anal sphincter and a need for colostomy.

Results
Local control, 60–80%; 60–90% 5-year survival; for larger lesions, RT and 5-FU and mitomycin are used. 

APR is less preferred than RT for small lesions + external beam treatment or with radioactive implants—e.g., 198Iridium seeds.

ab·dom·i·no·per·i·ne·al re·sec·tion

(ab-dom'i-nō-per-i-nē'ăl rē-sek'shŭn)
A surgical treatment for cancer involving resection of the lower sigmoid colon, rectum, anus, and surrounding skin, and formation of a sigmoid colostomy; performed as a synchronous or sequential transabdominal and perineal procedure.
References in periodicals archive ?
Abdominoperineal Resection (APR) is the surgical procedure done on patients with distal rectal cancer in which an anterior resection cannot be done to preserve anal sphincter or for anorectal cancer.
Additionally, this modality allows the surgeons to perform sphincter saving procedure instead of abdominoperineal resection and permanent ileostomy construction.
Low rectal cancer: a call for a change of approach in abdominoperineal resection.
Colorectal cancer involving the anal sphincter and refractory cases of UC (not amenable for IPAA) are routinely treated with abdominoperineal resection with anal closure [8].
In this case report, a new prone approach to a perineal urethrocutaneous fistula (UCF) arising after abdominoperineal resection (APR) is described.
6%) patients had abdominoperineal resection (APR) done as a surgical procedure.
Background: When compared with conventional abdominoperineal resection (APR), extralevator abdominoperineal excision (ELAPE) has been demonstrated to reduce the risk of local recurrence for the treatment of locally advanced low rectal cancer.
Abdominoperineal resection was applied for clearance of the pelvic space.
Emmanuel Tiret then showed live demonstration of Abdominoperineal Resection (APR) Anterior Resection.
sup][17],[18] In ACRT group, more patients underwent LAR than abdominoperineal resection (APR) under acceptable surgical risk due to lower abdominal pain after the operation and less complications, including bleeding, infection, and temporary difficulty with emptying the bladder.
Abdominoperineal resection is most appropriate for patients who are already incontinent with large bulky tumors extending into the sphincter muscle.
After receiving radiation and chemotherapy, the patient underwent abdominoperineal resection with removal of the sphincter muscle, resulting in a permanent colostomy.