abdominal perineal resectionThe surgical excision of the lower rectum and anus with the removal of the anal sphincter and placement of a colostomy.
Local control, 60–80%; 60–90% 5-year survival; for larger lesions, radiation therapy and 5-FU and mitomycin are added to the regimen.
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abdominal-perineal resectionSurgical oncology The surgical excision of the lower rectum and anus with loss of the anal sphincter and a need for colostomy. See Colostomy.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.