abasic


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a·ba·sic

(ă-bā'sik),
1. Affected by, or associated with, abasia.
2. Refers to loss of pyrimidine sites in DNA.
Synonym(s): abatic
Farlex Partner Medical Dictionary © Farlex 2012

a·ba·sic

, abatic (ă-bā'sik, ă-bat'ik)
1. Affected by, or associated with, abasia.
2. Refers to loss of pyrimidine sites in DNA.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

abasia

(a-ba'zh(e-)a) [ ¹an- + Gr. basis, step]
1. Motor incoordination in walking.
2. Inability to walk due to impairment of coordination. abasicabatic, adjective

abasia-astasia

Lack of motor coordination with inability to stand or walk. Synonym: astasia-abasia

paralytic abasia

Abasia in which the leg muscles are paralyzed.

paroxysmal trepidant abasia

Abasia caused by trembling and sudden stiffening of the legs on standing, making walking impossible. It may be related to hysteria.
Medical Dictionary, © 2009 Farlex and Partners
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References in periodicals archive ?
Korvald et al., "Sculpting of DNA at abasic sites by DNA glycosylase homolog mag2," Structure, vol.
Spotheim-Maurizot, "Radiation affects binding of Fpg repair protein to an abasic site containing DNA," Radiation Research, vol.
The Danish declaration has been rejected as being too one sided, while the version being circulated by the BASIC bloc is reportedly being merged with a declaration circulated by African countries (ABASIC).
Abasic network diagram looks a bit like a game of connect the dots that ends in a jumbled mess instead of a pretty picture.
ABASIC rail return to London will smash through the pounds 100 barrier in the New Year.
Abasic rate taxpayer saving this amount in a top-paying taxable account would lose around pounds 45 of the interest earned every year to the taxman, while a higher rate taxpayer could be charged pounds 90.
The in-store asking price of abasic model is $500 (pounds 250).
[35-38], and these earlier studies focused on the substitution of guanine for adenine, the introduction of abasic sites, 8-oxoadenine replacing adenine, and the substitution of 5-hydroxymethyluracil for thymine in telomeric repeats were analyzed [39-41].
HREs are subjected to oxidative damage leading the formation of an abasic site in one strand, and high sensitivity to oxidative damage of the terminal guanines in the HIF-1 target sequences has been reported [63].
Oxidative attacks by ROS on the deoxyribose moiety lead to the release of free bases from DNA, generating strand breaks with various sugar modifications and simple abasic sites (AP sites).
The N-glycosidic bonds of the purine bases to the sugar backbone are susceptible to hydrolysis at low pH (31), generating abasic sites in the DNA.