nonbacterial thrombotic endocarditis

(redirected from abacterial thrombotic endocarditis)

non·bac·te·ri·al throm·bot·ic en·do·car·di·tis

verrucous endocardial lesions occurring in the terminal stages of many chronic infectious and wasting diseases.

nonbacterial thrombotic endocarditis

Etymology: L, non + bakerion, small rod
one of the three main types of endocarditis, characterized by various kinds of lesions affecting the heart valves, most often on the left side of the heart. The disease may be the first step in the development of bacterial endocarditis, and the lesions may cause peripheral arterial embolisms, resulting in death. The disease equally affects men and women between 18 and 90 years of age and causes heart murmurs in about 30% of cases. There is no successful treatment, but anticoagulation therapy may be used to reduce the incidence of peripheral arterial embolism. See also Libman-Sacks endocarditis.
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Nonbacterial thrombotic endocarditis

nonbacterial thrombotic endocarditis

Abbreviation: NBTE
The presence on the heart valves of vegetations that are produced not by bacteria but by sterile collections of platelets in fibrin. NBTE is characteristically found in severe cases of systemic lupus erythematosus, tuberculosis, or malignancy. The vegetations of NBTE readily embolize, causing infarctions in other organs. Synonym: verrucous endocarditis
See also: endocarditis


exudative and proliferative inflammatory alterations of the endocardium, characterized by the presence of vegetations on the surface of the endocardium or in the endocardium itself, and most commonly involving a heart valve, but also affecting the inner lining of the cardiac chambers or the endocardium elsewhere.
Lesions on the valves may interfere with the ejection of blood from the heart by causing insufficiency or stenosis of the valves. Murmurs associated with the heart sounds are the major manifestation and if interference with the blood flow is sufficiently severe congestive heart failure develops. The further hazard with endocarditis, especially if it is bacterial in origin, is that of septic emboli in the lungs or in the other organs.

bacterial endocarditis
infectious endocarditis, acute or subacute, caused by various bacteria, including streptococci, staphylococci, enterococci and gram-negative bacilli. Of particular interest in animals is the predilection of Erysipelothrix rhusiopathiae to cause endocarditis, epecially in pigs.
ductal endocarditis
due to thrombosis in a persistent ductus arteriosus with resulting mural inflammation.
infectious endocarditis, infective endocarditis
that due to infection with microorganisms, especially bacteria and fungi.
mural endocarditis
that affecting the lining of the walls of the heart chambers only.
nonbacterial thrombotic endocarditis
that in which the vegetations, single or multiple, consist of fibrin and other blood elements.
parietal endocarditis
mural endocarditis.
tuberculous endocarditis
that resulting from extension of a tuberculous infection from the pericardium and myocardium.
valvular endocarditis
that affecting the membrane over the heart valves only.
vegetative endocarditis
endocarditis, infectious or noninfectious, the characteristic lesions of which are vegetations or verrucae on the endocardium. Called also verrucous endocarditis.