FGF1

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FGF1

A gene on chromosome 5q31 that encodes fibroblast growth factor 1 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF1 interacts with FGF receptors FGFR1, -2, -3 and -4.
References in periodicals archive ?
Although aFGF appears to have a role in the rat prostate, its importance in the human prostate has not been ratified.
3] Nonstandard abbreviations: PSA, prostate-specific antigen; AR, androgen receptor; AD, androgen dependent; AS, androgen sensitive; AI, androgen independent; KGF, keratinocyte growth factor; EGF, epidermal growth factor; IGF, insulin-like growth factor; IGF-BP, high-affinity IGF-specific binding protein; FGF, fibroblast growth factor; TGF, transforming growth factor; MPR, mouse prostate reconstitution; TbetaR, transforming growth factor-/3 receptor; bFGF, basic fibroblast growth factor; EGFR, epidermal growth factor receptor; FGFR, fibroblast growth factor receptor; aFGF, acidic fibroblast growth factor; and RA, retinoic acid.
AFGF is a limited liability company created under the laws of the State of Delaware.
O aFGF tem sido detectado na membrana de Descemet e no endotelio da cornea, mas em menor quantidade no epitelio.