FGF1

(redirected from aFGF)
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FGF1

A gene on chromosome 5q31 that encodes fibroblast growth factor 1 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF1 interacts with FGF receptors FGFR1, -2, -3 and -4.
References in periodicals archive ?
Zhao et al., "A thermosensitive heparinpoloxamer hydrogel bridges aFGF to treat spinal cord injury," ACS Applied Materials & Interfaces, vol.
Orally administrated aFGF induced angiogenesis in the ulcer bed and accelerated the healing of ulcers in animals 38].
laevis corneal explant cultures has shown that addition of FGFI protein, previously known as acidic FGF, or aFGF, to cornea explants induced the transdifferentiation of these cells into lens cells (Bosco et al., 1997b).
El objetivo de este estudio fue corroborar la eficacia del factor de crecimiento fibroblastico acido (aFGF) y el fibrin Glue (FG) como estimulantes de la regeneracion axonal y soporte anatomico en nuevo modelo experimental de trauma raquimedular.
Three members of this family, bFGF (FGF-2), acidic FGF (aFGF or FGF-1), and KGF (FGF-7) have been implicated in prostate cancer.
A switch in exon IIIb (which has a high affinity for KGF) of the FGFR gene to exon IIIc (with a high affinity for bFGF and aFGF) occurs in malignant epithelial cells as they become independent of their requirement for stroma (48).
LaVail, "Development of normal and injury-induced gene expression of aFGF, bFGF, CNTF, BDNF, GFAP and IGF-I in the rat retina," Experimental Eye Research, vol.
O FGF, que pode ser acido (aFGF) ou basico (bFGF), e mitogenico para as celulas epiteliais, endoteliais e estromais.