alpha-fucosidase

(redirected from a-fucosidase)

α-fu·co·si·dase

(fyū-kōs'i-dās),
An enzyme that catalyzes the hydrolysis of an an α-l-fucoside, producing an alcohol and l-fucose; a deficiency of the lysosomal enzyme will result in fucosidosis.
References in periodicals archive ?
Widespread angiokeratomas also occur in patients with several additional enzyme deficiencies, which include a-fucosidase (fucosidosis), neuraminidase (sialodosis), aspartylglucosaminidase (aspartylglucosaminuria), AY-mannosidase (AY- mannosidosis), a-N-acetylgalactosaminidase (Kanski disease), and AY-galactosidase (adult- onset GM1 gangliosidosis).13 Also, ACD may occur without recognizable enzyme deficiency,3,4 or as benign form without systemic features,5 or normal physical, mental development and with skin lesions alone.6
Widespread angiokeratomas also occur in patients with several additional enzyme deficiencies, which include a-fucosidase (fucosidosis), neuraminidase (sialodosis), aspartylglycosaminase (aspartylglucosaminuria), AY-mannosidase (AY- mannosidosis), a-N-acetylgalactosaminidase (Kansaki disease), and AY-galactosidase (adult- onset GM1 gangliosidosis).6