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An F-actin binding protein in vertebrate cells that cross-links actin filaments into regular parallel arrays. It is found in both the Z line and the I band of striated muscle.
References in periodicals archive ?
Together, talin and a-actinin help vinculin build tissues and organs out of individual cells by keeping cells in one spot, Izard said.
However, when the protein called a-actinin (alpha-actinin) binds to vinculin's head, the head acquires a different shape.
Positive staining of cardiac markers sarcomeric a-actinin and Nkx2.