alpha thalassemia

(redirected from a thalassemia)

α thal·as·se·mi·a

thalassemia due to one of two or more genes that depress (severely or moderately) synthesis of α-globin chains by the chromosome with the abnormal gene. Heterozygous state: severe type, thalassemia minor with 5-15% of Hb Bart at birth, only traces of Hb Bart in adult; mild type, 1-2% of Hb Bart at birth, not detectable in adult. Homozygous state: severe type, erythroblastosis fetalis and fetal death, only Hb Bart and Hb H present; mild type not clinically defined.
See also: hemoglobin H.
References in periodicals archive ?
LAHORE -- The Blood Donor Society of the University of Veterinary and Animal Sciences (UVAS), in collaboration with Kashif Iqbal Thalassemia Care Centre (KITCC), observed the Red Day, organised a thalassemia awareness seminar with the aim of making the country thalassemia free.
Uquali announced to bear the outlay of a Thalassemia major patient from his personal profit for a whole of his life adding that the provision of the funds to Thalassemia Center Badin for solar lights from the fund generated through street gain campaign was an exemplary service of Sindh Doctors Association of UK.
It was reported that monthly average treatment cost of a thalassemia patient in Pakistan was about Rs.
As family and same caste marriages are very common in Pakistan, without screening it can be considered that any married couple who are closely or distantly related to a thalassemia patient can be carriers of thalassemic gene.
He urged that a Thalassemia Protection Bill should be implemented in KP province under which free of cost thalassemia test should be arranged at all DHQs and THQs to prevent the further increase in figure of the disease.
11 The diagnosis and management of a thalassemia may be complex by the heterogeneity of diseases, which is due to the interaction of coinherited a-thalassemia with the variable severity of b-thalassemia mutations.
If these individuals are not made aware of the challenges they may face during reproduction, they may have to face the misery of supporting a thalassemia patient.
A Thalassemia screening drive for PSO employees was also held.
When they marry a non-carrier, the child born may also be a Thalassemia minor patient.
Mirah, a Thalassemia Centre patient, was crowned "Snow White" princess for one day.
Pre-marital check Pre-marital blood tests are an important preventive step for Thalassemia, which minimize the possibility of becoming a Thalassemia victim, according to the Yemeni Association for Thalassemia.
Seroprevalence of hepatitis B, hepatitis C, and HIV in multiple transfused thalassemia patients: results from a thalassemia day care centre in Malaysia.