alpha thalassemia

(redirected from a thalassemia)

α thal·as·se·mi·a

thalassemia due to one of two or more genes that depress (severely or moderately) synthesis of α-globin chains by the chromosome with the abnormal gene. Heterozygous state: severe type, thalassemia minor with 5-15% of Hb Bart at birth, only traces of Hb Bart in adult; mild type, 1-2% of Hb Bart at birth, not detectable in adult. Homozygous state: severe type, erythroblastosis fetalis and fetal death, only Hb Bart and Hb H present; mild type not clinically defined.
See also: hemoglobin H.
References in periodicals archive ?
Visit www.thewishingfactory.org or call 844-844-9544 to schedule a Thalassemia test and to donate to help patients," it further read.
The meeting was told that a Thalassemia Registry would be established in which all thalassemia major patients would be registered.
The meeting was told that a Thalassemia Registry shall be established in which all Thalassemia major patients would be registered.
'Our purpose is a thalassemia major free Pakistan,' stated Dr Bhambha, sharing that more than 5,000 children are suffering from thalassemia major while 17% suffer from thalassemia minor.
According to Bangladesh Thalassemia Foundation (BTF), a Thalassemia patient needs 1-2 bags of blood every month to survive and the disease is very common in Bangladesh.
Uquali announced to bear the outlay of a Thalassemia major patient from his personal profit for a whole of his life adding that the provision of the funds to Thalassemia Center Badin for solar lights from the fund generated through street gain campaign was an exemplary service of Sindh Doctors Association of UK.
It was reported that monthly average treatment cost of a thalassemia patient in Pakistan was about Rs.
As family and same caste marriages are very common in Pakistan, without screening it can be considered that any married couple who are closely or distantly related to a thalassemia patient can be carriers of thalassemic gene.
He urged that a Thalassemia Protection Bill should be implemented in KP province under which free of cost thalassemia test should be arranged at all DHQs and THQs to prevent the further increase in figure of the disease.
A Thalassemia screening drive for PSO employees was also held.
This mutation also activates a cryptic mRNA splice site, which results in reduced synthesis of the [beta]-E chain and leads to a thalassemia phenotype.
Pre-marital check Pre-marital blood tests are an important preventive step for Thalassemia, which minimize the possibility of becoming a Thalassemia victim, according to the Yemeni Association for Thalassemia.