These figures are hence identical to those reported by Howanitz et al, (1) since a hemolysis
rate below 2.9% was observed in exactly 71% of laboratories in both the ESAB and College of American Pathologists (CAP) surveys.
The prevalence of a hemolysis
after PDA endocarditis is unknown.
index of 150 arbitrary units (AU), in one published study, was equivalent to a hemoglobin concentration of 19.0 g/dl (1 g/L), within the sample .
Since adopting the best practices in 2009, Sarasota Memorial has successfully maintained a hemolysis
rate of less than 1 percent overall across the health system - a rate well below the national average of 5-7 percent.*
According to laboratory protocol, a hemolysis
level corresponding to an approximate hemoglobin concentration below 100 mg/dL is judged to be acceptable for testing.
For both assays, a hemolysis
index of around 150 caused a > 20% change in cTn (Fig.
QI have been trying to find a hemolysis
control for our COBAS INTEGRA and have been unsuccessful.
In conclusion, a hemolysis
rate of 28.6% (4571 of 15 978) suggests that this is the best performance these units can achieve and can be considered as a new acceptable threshold for hemolyzed specimens from neonatal units in our institution.
The hemoglobin concentration was measured as a hemolysis
index (HI) (calibrated in milligrams per deciliter hemoglobin) on the Abbott c8000 analyzer.
It is possible that an individual department may have a hemolysis
rate comparable to the ED rate; however, total specimen numbers for each department were not captured.
It is reasonable to expect a hemolysis
rate of less than 2%.
If the difference between potassium concentrations in samples with a hemolysis
index of 0 and those with a hemolysis
index of 1 through 10 was not significant, as assessed by using the above formula, then hemolysis was considered not to be clinically significant.