Patient discussion about genetic

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Q. Are there genetic factors involving allergies?

My entire family suffers from different allergies. It is clear that there is a connection, is that true?
A1The risk of allergic sensitization and the development of allergies varies with age, with young children most at risk. It is known that there is a strong genetic relation and allergies are usually common among family members. Ethnicity may play a role in some allergies, however racial factors have been difficult to separate from environmental influences and changes due to migration.
A2Yes, allergic diseases are strongly familial. I are likely to have the same allergic diseases about 70% of the time; the same allergy occurs about 40% of the time in non-identical twins. Allergic parents are more likely to have allergic children, and their allergies are likely to be more severe than those from non-allergic parents. Some allergies, however, are not consistent along genes. Parents who are allergic to peanuts may have children who are allergic to ragweed. It seems that the likelihood of developing allergies is inherited and related to an irregularity in the immune system, but the specific allergen is not.
A3there is a great connection. but it's not unlikely that it's genetic and environmental in your family... to try and figure this out you can see if there were allergies in the family way back. here's something to think about:

Q. Is celiac genetic?

I have one son with celiac disease from my first marriage and me second wife is now pregnant,I was wondering what are the chances for this soon to be born daughter of mine to have celiac as well- if I maybe carry the genetic flaw and is there a way to find out?
ACeliac disease is a very common illness (about 1 in a 100 people suffer from it in different levels), and it is known to have a strong genetic connection. However, there is not one specific mutation that you can get genetic testing to see if you are carrying it. Your soon to be born daughter will have a higher chance than the regular population to suffer from the disease, but it does not necessarily mean she will.

Q. is Bipolar genetic?

A1Bipolar disorder has a very strong genetic background: The approximate lifetime risk of this disease in relatives of a bipolar patient is 40 to 70 percent for a monozygotic (identical) twin and 5 to 10 percent for a first degree relative, compared with 0.5 to 1.5 percent for an unrelated person.
A2Bipolar is under "neurology" not under "genetics." But Bipolar cause may stem from "heredity," "environmental factors" or "chemical imblances in the brain."

Q. Is bipolar genetic?

and if it is, can I still get it if my parents don't have it??
A1thanks guys you're great, actually its not me I'm worried about, it's my brother. he keeps having serious fluctuations in his mood and it's getting harder and harder to communoicate with him- though before we had the most amazing relationship. what should I do?
A2It is possible to develop symptoms of bipolar disorder even if your parents dont have the illness. There is always a chance of a family history of the illness. Historically a lot of people were misdiagnosed with other mental disorders or not diagnosed at all. There is also environmental factors to this illness, like dagmar said. If you are showing symptoms the best thing to do is to go see your doctor and get a referral to see a psychiatrist for a diagnosis. The earlier you can be diagnosed the better and if you do not have bipolar disorder your question will be answered and you can go on with life not worrying about it.
A3Yes, it has a strong genetic component (i.e. the tendecy to develop it depends not only on environmental exposure but also on genetic predisposition_, although it's not a pure genetic disease, e.g. even if one has the predisposing genetic make-up he or she may not develop the disease (unlike pure genetic disease such as CF or Tay-Sachs, etc.)

Q. Is there a connection between ADHD and genetics?

I have a sister who has ADHD since she was a child. I was wondering if this is a genetic disorder.
A1The broad selection of targets indicates that ADHD does not follow the traditional model of a "genetic disease" and should be viewed as a complex interaction among genetic and environmental factors. However, there is yet a strong connection between this syndrome and genetics. Even though all these genes might play a role to date no single gene has been shown to make a major contribution to ADHD. Candidate genes include dopamine transporter, dopamine receptor D4, dopamine beta-hydroxylase, and more.
A2There is indeed a genetic basis to ADHD or ADD. Twin studies indicate that the disorder is highly heritable and that genetics cause about 75% of ADHD cases. Hyperactivity also seems to be primarily a genetic condition however other causes do have an effect. Researchers believe that a large majority of ADHD arises from a combination of various genes, many of which affect dopamine transporters.

Q. what makes Arthritis a genetic disease?

AFirst of all, the term arthritis is a bit inaccurate: Arthritis denotes an inflammation of joints. There are many kinds of arthritis that may result from different causes, and therefore, are different diseases: septic arthritis (inflammation due to infection of joint) has much less genetic background than ankylosing spondylitis (an arthritis of the lower back joints that occurs almost exclusively in people with certain genetic background).

The arthritis with the genetic background are usually the autoimmune ones: Due to genetic determinants, the immune system of some people is programmed to recognize the various parts of the joints (and other organs as well) as foreign (i.e. like bacteria) and thus launches an attack on them. In normal immune system, that doesn't happen.

You may read more here:

Q. Is bipolar disorder genetic or environmental?

Does anyone know why it seems that all the mental disorders involve chemical imbalances, like the dopamine hypothesis, and serotonin and all that? Psychologists always say its Genetics, though it really seems environmental factors play the biggest role. I honestly think that almost all personality, mood, and psychotic disorders are not cause by genetics, but the way people were raised and the kind of life they lead
ALike always the answer is complicated…when I looked it up in PubMed I found articles that proved it to be genetic and some that proved it to be environmental. Let’s just say that if you have the genetic tendency to develop bipolar syndrome- all you need is an environmental trigger.
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