Patient discussion about familial Mediterranean fever

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Q. Can Familial Mediterranean Fever (FMF) cause a heart enlargement?

A friend of mine is suffering from FMF. its usually doesn't bother him that much and when it dose the symptoms are stomach ache and fever. he has no heart symptoms and takes no medications. his physician told him that because of the FMF he might suffer from a heart enlargement, and that he should take some oral medications daily to prevent it. how can it be?
A1This question can't be answered with a strict yes or no.
although FMF on its own can't cause heart enlargement, FMF can cause amyloidosis because of the recurrent inflammation. this may lead to enlargement of the heart which is a severe disease.
the good side is that taking medication can decrease the chance of the cardiac enlargement.
A2The answer is yes.
FMF is a systemic disease. the usual symptoms of FMF are truly fever and abdominal pain, but this are just signs for the illness inside.
All the fever and pain encourage our body to create some kind of proteins that can sink in the heart muscle and make it thicker and cause a lot of heart problems.
enlargement of the heart is one of those problems.
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