Some specific subjects examined are the biochemical activities of the HCV NS5B RNA-dependent RNA polymerase, HCV replicon systems, HCV regulation of
host defense, and recombinant vesicular stomatitis virus (VSV).
Antimicrobial proteins play an important role in human
host defense. Defensin, chemerin and hepcidin are among antimicrobial proteins.4 Especially hepcidin that among these hormones, is an peptide associated with iron metabolism.
The airway epithelium has a range of properties that contribute to lung defense, including constitutive
host defense mechanisms and regulation of airway innate immunity.
Historically, our view of
host defense against infection was that we must eliminate pathogens to eradicate the disease.
"These findings show a new role for skin commensal bacteria in
host defense," the authors write.
This evidence substantiates that dietary Zn uptake is important in maintaining homeostasis, proper innate immune balance, and
host defense [13].
Lymphopenia is an abnormally low level of lymphocytes, or white blood cells, that manage microbial
host defense.
Mucociliary clearance represents a
host defense mechanism of airways that can be compromised by various pathologic conditions, such as nasal septal deviation.
Surfactant protein-D and pulmonary
host defense. Respir Res.
These compounds mimic the
host defense proteins of the innate immune system, and therefore, have both antibacterial and immunomodulatory properties.
These peptides represent not only an important component of innate
host defense against microbial colonization and a link between innate and adaptive immunity, but also form a foundation for the development of new therapeutic agents.