Mayo Risk Score

A decision-making model for primary biliary cirrhosis and primary sclerosing cholangitis based on five variables—three lab parameters (serum BR levels, serum albumin levels and prothrombin time), patient age and severity of oedema and/or ascites—which allows prognostication. The Mayo Risk Score provides accurate information about the patient’s prognosis.

The Mayo Risk Score
(R)   =   (0.0295 * (age in years))
          + (0.5373 * LN(total bilirubin in mg/dL))
          – (0.8389 * (serum albumin in g/dL))
          + (0.5380 * LN(AST in IU/L)
          + (1.2426 * (points for variceal bleeding))
where:
LN indicates the natural logarithm; and
AST = serum aspartate aminotransferase level.

Points for variceal bleeding: 0 if none, 1 if present. Each unit increase in the Mayo Risk Score (R) is associated with a 2.5-fold increase in the risk of death; most references to the score round the coefficients to 2 decimal places.

The score shows very slight upward slope over time in stable patients, but during the terminal phase it shows an acceleration in progression.

Mentioned in

score

References in periodicals archive

Mayo Risk Score (MRS) was used for the evaluation of patients with Primary biliary cirrhosis and primary sclerosing cholangitis which has been validated using independent data sets at different institutions15.

Milan's Criteria was used for hepatocellular carcinoma and Mayo risk scores (MRS) for patients with Primary Biliary Cirrhosis and Primary Sclerosing Cholangits.

Patients of primary biliary cirrhosis and primary sclerosing cholangits were evaluated on the basis of Mayo Risk Scores while in cases of hepatocellular carcinoma, patients meeting United Network for Organ Sharing (UNOS) criteria (1 lesion 2-5 cm or 2 to 3 lesions less than 3 cm) were considered eligible for priority listing.

ASSESSMENT OF PATIENTS WITH CHRONIC LIVER DISEASE QUALIFYING FOR LIVER TRANSPLANT

All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.