Zinga

(redirected from Zynga)
Also found in: Encyclopedia.

nizatidine

Apo-Nizatidine, Axid, Axid AR, Dom-Nizatidine, Gen-Nizatidine, Novo-Nizatidine, PHL-Nizatidine, PMS-Nizatidine, Zinga (UK)

Pharmacologic class: Histamine2 (H2)-receptor antagonist

Therapeutic class: Antiulcer drug

Pregnancy risk category B

Action

Inhibits histamine action at H2-receptor sites in gastric parietal cells, reducing gastric acid secretion and pepsin production

Availability

Capsules: 150 mg, 300 mg

Oral solution: 15 mg/ml

Tablets: 75 mg

Indications and dosages

Active duodenal ulcer Adults: 300 mg P.O. daily at bedtime or 150 mg b.i.d. for up to 8 weeks

Maintenance of healed duodenal ulcers

Adults and children ages 12 and older: 150 mg P.O. daily at bedtime for up to 1 year

Esophagitis and associated heartburn caused by gastroesophageal reflux disease (GERD)

Adults: 150 mg P.O. b.i.d. for up to 12 weeks

Active benign gastric ulcer Adults: 150 mg P.O. b.i.d. or 300 mg P.O. once daily at bedtime

Erosive esophagitis; GERD

Children ages 12 and older: 150 mg P.O. b.i.d. for up to 8 weeks

Dosage adjustment

• Moderate to severe renal impairment

• Elderly patients

Contraindications

• Hypersensitivity to drug or other H2-receptor antagonists

Precautions

Use cautiously in:

• mild renal impairment

• elderly patients

• pregnant or breastfeeding patients

• children younger than age 12 (safety and efficacy not established).

Administration

• Give with or without food.

• If patient is to take drug twice daily, give one dose in morning and one at bedtime.

Adverse reactions

CNS: dizziness, drowsiness, headache, anxiety, nervousness, insomnia, abnormal dreams, asthenia

CV: chest pain

EENT: amblyopia, sinusitis, rhinitis, pharyngitis

GI: nausea, vomiting, diarrhea, constipation, dyspepsia, abdominal pain, flatulence, anorexia, dry mouth

Hematologic: anemia

Musculoskeletal: back pain, myalgia

Respiratory: cough

Skin: rash, pruritus

Other: tooth disorder, infection, fever, pain

Interactions

Drug-drug. Salicylates (high doses): increased salicylate blood level

Drug-diagnostic tests. Alanine amino-transferase, alkaline phosphatase, aspartate aminotransferase: elevated levels

Urobilinogen tests using Multistix: false-positive result

Drug-herbs. Pennyroyal: altered rate of herbal metabolite formation

Patient monitoring

• Monitor liver and renal function tests.

• Check temperature; watch for fever and other signs and symptoms of infection.

Patient teaching

• Advise patient to take once-daily dose at bedtime with or without food, or twice-daily doses in morning and at bedtime.

• Instruct patient to take exactly as prescribed. Caution him not to take other OTC drugs (especially aspirin).

• Tell patient to report signs and symptoms of infection.

• Caution patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness.

• As appropriate, review all other significant adverse reactions and interactions, especially those related to the drugs, tests, and herbs mentioned above.

Zinga

A brand name for NIZATIDINE.
Mentioned in ?
References in periodicals archive ?
In his opinion, Bouchard also dismissed allegations that Goldman Sachs & Co and Morgan Stanley had done anything wrong by collecting fees from Zynga when it lifted lockups for the executive investors.
According to Mashable, the announcement comes just seven months after Zynga unexpectedly laid off more than 500 employees and shut down three offices at the same time.
Zynga is responsible for the popular games "Words With Friends," "Chess With Friends" and "Scramble With Friends," and claims that Bang With Friends Inc.
"Today is a hard day for Zynga and an emotional one for every employee of our company," founder Mark Pincus said in a blog post as the company cut 520 jobs and closed several of the San Francisco-based company's studios.
Apart from shutting down these games, Zynga CEO Mark Pincus says the company has decided to cancel work on the development of two of its unreleased games.
The surprise twist is that Zynga is not in the top five this year.
"Zynga's mission is to connect the world through games," Barry Cottle, Zynga's chief revenue officer, said in a statement.
Mail.ru's minority investments, Groupon, Zynga and Facebook, all held IPOs on NASDAQ in 2011-2012.
After closing the first day at $9.50, Zynga managed to peak at $14 on March 7.
Only this was not a traditional Vegas-esque gaming firm, it was the social online gaming giant Zynga -- otherwise known as the creators of FarmVille, CityVille and Words With Friends.
BANKING AND CREDIT NEWS-March 14, 2012--M Stanley, Goldman to run Zynga's follow-on stock offering(C)2012 M2 COMMUNICATIONS http://www.m2.com
This one-day developer event will be hosted with Zynga at their new offices in Bangalore.