Zinc Finger Protein

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Any of a superfamily of transactivating protein receptors that mediate the actions of steroids and steroid-like hormones; after a zinc finger receptor binds a hormone, it influences gene expression by associating with specific DNA elements, the hormone-responsive elements (HREs)


a chemical element, atomic number 30, atomic weight 65.37, symbol Zn. See Table 6.
Zinc is a trace element that is a component of several enzymes, including DNA and RNA polymerases, and carbonic anhydrase. Zinc salts are used in skin lotions, eye washes, the treatment and prevention of footrot of sheep and facial eczema of sheep and cattle.

zinc acetate
a salt used as an astringent and styptic.
zinc cadmium sulfide
used in the preparation of fluoroscopic screens; is fluorescent and emits yellow-green light when excited by x-rays.
zinc carbonate
a mild astringent; used mainly as calamine.
zinc chromate
an industrial compound used in cold galvanizing of metal. Accidental access causes diarrhea and fatal enteritis.
zinc finger motif
sequence of approximately 30 amino acids, forming a helix-turn-helix, believed to form a structure that includes tetrahedrally coordinated zinc (II) ions. Found in many eukaryotic, prokaryotic and viral DNA-binding proteins.
zinc finger protein
DNA-binding proteins that contain zinc-finger motifs.
zinc gelatin
a mixture of zinc oxide, gelatin, glycerin and purified water; used topically as a protectant.
zinc gluconate
a source of supplementary zinc.
hereditary zinc deficiency
lethal trait A46; see inherited parakeratosis.
zinc nutritional deficiency
causes parakeratosis in pigs, a chronic, afebrile, noninflammatory disease of the epidermis characterized by crusty proliferation and cracking of the skin. Dogs fed diets with high levels of calcium or cereals may have poor absorption of zinc and develop signs of deficiency, primarily in the skin. See also zinc-responsive dermatosis.
zinc ointment
a preparation of zinc oxide and mineral oil in white ointment; used topically as an astringent and protectant.
zinc oversupplementation
causes hemolytic anemia, anorexia and vomiting.
zinc oxide
a compound used as a topical astringent and protectant. Inhalation of fumes causes interstitial emphysema and atelectasis.
zinc phosphate
used as a phosphate-bonded cement in restorative dentistry.
zinc phosphide
used at one time as a rodenticide. When ingested the poisonous gas phosphine is liberated and kills the animal without diagnostic signs or lesions.
zinc poisoning
is usually chronic and causes stiffness and lameness with particular involvement of the shoulder joint in which there is a degenerative arthritis. In acute poisoning there is gastroenteritis with vomiting.
zinc-responsive dermatoses
see parakeratosis, zinc-responsive dermatosis.
zinc stearate
a compound of zinc with stearic and palmitic acids; used as a water-repellent protective powder in dermatoses.
zinc sulfate
a compound used as an ophthalmic astringent, in skin lotions (see white lotion), for sheep footrot, and the treatment of facial eczema. It is the common form of zinc for oral supplementation and treatment of zinc-responsive diseases.
zinc sulfate flotation test
used to demonstrate nematode eggs, protozoan cysts, and larvae in feces and bronchial secretions.
zinc sulfate turbidity test
1. serum globulins are precipitated by zinc sulfate. The test is used for the semiquantitative assessment of the immunological status of foals and calves when there is a question of whether they have suckled to receive immunoglubulins.
2. an outdated liver function test.
zinc undecylenate
a compound used topically in 20% ointment as an antifungal agent. See also undecylenic acid.
References in periodicals archive ?
We did all our tests in mouse cells because they lack all of the primate zinc finger proteins, so when you put primate retrotransposons into a mouse cell they're all active," Salama explained.
Hunchback-like (Hb) proteins represent a subgroup of a large and diverse family of zinc finger proteins present in eukaryotic bilaterian genomes (Lander et al.
Proteins identified Accession (a) Downregulated proteins 1 PRAME family member 7 PRAM7_HUMAN 2 [alpha]-1B-glycoprotein precursor A1BG_HUMAN 3 Keratin, type II cytoskeletal 1 K2C1_HUMAN 4 Neurofilament triplet L protein NFL_HUMAN 5 Vitamin D-binding protein VTDB_HUMAN precursor 6 Protease C1 inhibitor IC1_HUMAN precursor 7 Keratin, type I cytoskeletal 10 K1C10_HUMAN 8 Complement factor B CFAB_HUMAN precursor 9 Complement C1r C1R_HUMAN subcomponent precursor 10 Transthyretin precursor TTHY_HUMAN 11 Zinc finger protein 792 ZN792_HUMAN 12 Kininogen-1 precursor KNG1_HUMAN Upregulated proteins 1 Complement factor H CFAH_HUMAN precursor 2 Apolipoprotein C-III precursor APOC3_HUMAN 3 [[alpha].
Lead inhibition of DNA-binding mechanisms of Cys2His2 zinc finger proteins.
The firm also supplies ready-made and custom-made zinc finger proteins to scientists around the world.
Among the topics are microfluidic applications in vascular bioengineering, social and ethical concerns of biomedical engineering research and practice, biomedical watermarking, handling large medical data sets for disease detection, regional and community health information exchange in the US, medical transcription as a pioneer in healthcare informatics, artificial intelligence in medical fields, and analyzing and predicting DNA recognition by zinc finger proteins with applications in genome modification.
Interestingly, the numerous cysteines of ORFX are in the same domain organization than zinc finger proteins (ZF1 and ZF2 in Fig.

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