omeprazole

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Related to Zegerid: Zegerid OTC

omeprazole

 [o-mep´ra-zōl]
a proton pump inhibitor, used in treatment of dyspepsia, gastroesophageal reflux disease, disorders of gastric hypersecretion, and peptic ulcer, including that associated with Helicobacter pylori infection; administered orally.

omeprazole

(ō-mĕp′rə-zōl′)
n.
A proton pump inhibitor drug, C17H19N3O3S, that suppresses gastric acid secretion and is used for the treatment of duodenal and gastric ulcers and gastroesophageal reflux disease.

omeprazole

Prilosec® Therapeutics A proton pump inhibitor used to manage GERD; heartburn; erosive esophagitis; maintenance of healed erosive esophagitis; short-term management of active duodenal ulcer and active benign gastric ulcer, and for certain hypersecretory conditions; combined with clarithromycin to eradicate H pylori associated with duodenal ulcers. See GERD, Helicobacter pylori. Cf H2 blockers.

omeprazole

The first of the class of proton pump inhibitor drugs used to control the production of stomach acid and treat stomach and duodenal ulcers and especially the ZOLLINGER-ELLISON SYNDROME. OMEPRAZOLE can be effective in cases that have failed to respond to H-2 receptor blocker drugs such as RANITIDINE. The drug is long-acting and need only be taken once a day. A brand name is Losec.
References in periodicals archive ?
Indicated for the treatment of frequent heartburn, Zegerid OTC employs the dual action of omeprazole, a proton pump inhibitor that lowers the amount of acid in the stomach, and sodium bicarbonate, an antacid that raises the stomach's pH level to prevent the omeprazole from breaking down in stomach acid.
The company said Zegerid OTC (omeprazole and sodium bicarbonate capsules, 20mg/1100mg) is indicated for the treatment of frequent heartburn.
For the most recent 12 months ending in May 2016, the Zegerid brand and generic had US sales of approximately USD306.7m MAT, according to IMS Health.
Now, the company's product portfolio offers 22 marketed products, including XIFAXAN, UCERIS, GLUMETZA, APRISO, ZEGERID, MOVIPREP, RELISTOR, SOLESTA, FULYZAQ, CYCLOSET and DEFLUX.
However, some people take PPIs (Prilosec, Prevacid, Zegerid, Nexium) for months, and even years, without being evaluated for GERD, and recent research shows that many could stop taking PPIs and save a great deal of money if they underwent testing.
Two proton pump inhibitors, lansoprazole (Prevacid) and omeprazole (Prilosec, Zegerid), are the antisecretory agents of choice for H.
Perrigo Co., for example, released lansoprazole capsules, a bio-equivalent to Novartis AG's Prevacid 24HR capsules, and omeprazole and sodium bicarbonate capsules, a generic version of Merck & Co's Zegerid, in 2012.
According to Perrigo, its OTC version of Omeprazole and Sodium Bicarbonate Capsules is the store brand equivalent to Merck & Co's Zegerid OTC, a proton pump inhibitor indicated to relieve frequent heartburn, which over the last 12 months recorded sales of about USD42m through food, drug and mass merchandisers.
(All PPI packaging will now carry a written warning.) This news is of particular concern for postmenopausal women who take a PPI such as Nexium, Prilosec, Zegerid, or Aciphex, and are at risk of osteoporosis and fracture.
(+0.9%) Market Dollar sales Dollar sales LEADING BRANDS ** share (000) % change Private Label 40.4% $62,954 - 3.9% Prilosec OTC 16.1% 25,010 - 9.4% Zantac 150 6.8% 10,650 + 12.1% Prevacid 24HR 4.9% 7,564 - 7.3% Gas X 3.5% 5,488 + 0.9% Pepcid AC 3.2% 5,050 + 2.9% Tums 2.8% 4,327 - 13.8% Tums Ultra 2.3% 3,564 + 3.9% Pepcid Complete 2.2% 3,348 + 54.1% Zegerid OTC 1.9% 3,017 - 3.4% TOTAL UNIT SALES * 58 mil.
The decrease in revenues resulted primarily from a decrease in net product sales of ZEGERID brand products due to generic competition for ZEGERID Capsules prescription products.
More recently, Novartis Consumer Healthcare Inc.'s Prevacid followed that path, as did Zegerid from Merck & Co.