Zaire virus

Zaire virus

(zah-ēr'),
a variant of Ebola virus.
Synonym(s): Ebola virus Zaire

Za·ire vi·rus

(zī-ēr' vī'rŭs)
A variant of Ebola virus.
Synonym(s): Ebola virus Zaire.
Mentioned in ?
References in periodicals archive ?
Cause: Five strains of Ebola virus have been identified 6 Bundibugyo virus, Sudan virus, Tai Forest virus, Zaire virus and Reston virus.
Developed by scientists at the PHAC's National Microbiology Laboratory and based on the same platform used to produce Merck's successful Ebola Zaire virus vaccine, this candidate provided high-level protection from Lassa fever virus in previously conducted animal studies.
It was reported yesterday that the agreement has potential future options totalling USD6.3m to support the development of vaccines against filovirus species including Marburg and Ebola Sudan viruses, which could be combined with Ebola Zaire virus in a multivalent vaccine formulation or vaccination schedule.
Zaire virus is most dangerous known EVD causing specie.
- US-based diagnostic test developer Cepheid (NASDAQ: CPHD) has received Emergency Use Authorization from the US Food and Drug Administration for Xpert Ebola, a molecular diagnostic test for Ebola Zaire Virus that delivers results in less than two hours.
The experimental vaccines now moving into large clinical trials in West Africa target the current Ebola Zaire virus strain, but the next outbreak may be different.
Synthetic constructed mouse CpG motifs showed a 100% successful prevention of mouse-adapted EBOV lethality when injected intraperitoneally either 24 hours before or 24 hours after a lethal challenge with mouse-adapted Ebola Zaire virus. Identical results were achieved in guinea pigs when injected with synthetic constructed guinea pig CpG motifs and challenged with a 100% lethal Ebola Zaire virus titer, (77) as first noted by S.J.
Food and Drug Administration (FDA) officials recently issued an emergency use authorization (EUA) for Utah-based BioFire Defense LLC's FilmArray Biothreat-E test for the detection of the Ebola Zaire virus. The test runs and can only be used with the device maker's FilmArray systems.
Bukreyev's research group made the discovery after a series of procedures that started with a clone of the Ebola Zaire virus strain.
Potentially positive serum samples were tested by ELISA against each nucleoprotein independently to confirm reactivity and by Western blotting against nucleoproteins of Reston and Zaire virus strains as described (10).
The Zaire virus is the type species, which is also the first discovered and the most lethal.