ZBTB10

ZBTB10

A gene on chromosome 8q13-q21.1 that encodes a protein thought to be involved in regulating transcription.
References in periodicals archive ?
Por otra parte, miR-27a fue reportado en cancer de seno como un oncomiR que regula el gen ZBTB10 (zinc finger and BTB domain containing 10), un represor de proteinas especificas oncogenicas (Sp).
Transfection of MDA-MB-231 cells with anti-miR-27a has been associated with increased ZBTB10 mRNA expression; reduced expression of Sp1, Sp3, and Sp4 at mRNA and protein levels; and reduced Sp-dependent survival and angiogenic genes, findings that support the proposed oncogenic properties of miR-27a (38).
5] Genes: PDCD4, programmed cell death 4 (neoplastic transformation inhibitor); TPM1, tropomyosin 1 (alpha); PTEN, phosphatase and tensin homolog; TIMP3, TIMP metallopeptidase inhibitor 3; SOCS1, suppressor of cytokine signaling 1; ZBTB10, zinc finger and BTB domain containing 10; RHOC, ras homolog gene family, member C; CD44, CD44 molecule (Indian blood group);BRMS1, breast cancer metastasis suppressor 1; SOX4, SRY (sex determining region Y)-box 4; TNC, tenascin C; CDC42, cell division cycle 42 (GTP binding protein, 25kDa); CXCR4, chemokine (C-X-C motif) receptor 4; CYP19A1, cytochrome P450, family 19, subfamily A, polypeptide 1.