yessotoxin

(redirected from YTX)
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yessotoxin

(yes″ō-tok′sĭn),

YTX

A poisonous disulfated polyether produced by marine algae. It causes heart and liver damage in people who ingest shellfish that have fed on the algae.
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For that, Caco-2 cells were exposed to 3 and 9 nM of all the toxins, including the analogues, except for YTX, for which 12.5 and 37.5 nM were used.
Also, the profiles of OA, DTX-1, and DTX-2 were identical as were the profiles of YTX and hYTX.
Also included in the lipophilic pectenotoxins (PTXs), yessotoxins (YTXs), spirolides (SPXs) and azaspiracids (AZPs).
The PST was detected only in the plankton (Table 3) and the YTXs only in the shellfish (Figs.
The individual scans of detected compounds OA, DTX-1, and YTX are shown in Figure 6; other monitored analytes were below the limits of detection.
Okadaic acid was the next most abundant, accounting for less than 6%, followed by small amounts of YTX, PTX-2, and AZA-2.
Selective reaction monitoring LC-MS/MS chromatograms for the OA and YTX standards and the cleaned-up methanol extract of the abalone digestive gland (4.7 ng/g OA and 1.3 ng/g YTX) are shown in Figure 1.
Retention times for OA (11.3 min) and YTX (12.8 min) obtained from the abalone digestive gland extract matched exactly those recorded for authentic toxin standards.
Meanwhile, the production of YTX by the dinoflagellate P.
Many different YTX analogues were detected until now, but of about 100 YTXs, only 40% are characterized concerning their exact chemical structure (Paz et al.
SRM LC-MS/MS analysis for toxins was carried out using [[M-H].sup.-] (OA, DTX1, YTX) or [[M + HCOOH-H].sup.-] (PTX2) as the target parent ions in Q1 and particular fragment ions of each toxin in Q3.