STK25

(redirected from YSK1)

STK25

A gene on chromosome 2q37.3 that encodes a ubiquitously expressed serine/threonine-protein kinase activated in response to oxidant stress, which thus may play a role in the response to environmental stress. It is phosphorylated upon DNA damage, probably by ATM or ATR, and targets to the Golgi apparatus where it is thought to regulate protein transport, cell adhesion and polarity complexes, which are important for cell migration.
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References in periodicals archive ?
The MST kinase family, which is related to the Hippo kinase in Drosophila melanogaster, consists of five related proteins: STK3 (also known as MST2), STK4 (also known as MST1), STK24 (also known as MST3), STK25 (also known as YSK1), and STK26 (also known as MST4) [19].