In the xenograft
, alloplastic graft 1 and alloplastic graft 2 groups, characteristics that were similar to those of the control group in new bone formation.
Furthermore, representative H&E-stained tumor xenograft
sections showed that on day 7 after the ethanol injection, the tumor xenografts
had a large area of necrosis in the 80% ethanol group, but there was no necrotic or damaged region in the control group (Figure 5).
First in vivo studies using HT-29 xenografts
showed insufficient tumor uptake.
Establishment of genetically diverse patient-derived xenografts
of colorectal cancer.
Advances in patient-derived tumor xenografts
: From target identification to predicting clinical response rates in oncology.
Origin of the vasculature supporting growth of primary patient tumor xenografts
. Journal of translational medicine.
Compared to the control group, a significant number of TUNEL positive cells appeared after MTE (20 g/kg) treatment both in H460 and HI 975 xenografts
(p < 0.001 vs control), indicating the presence of an elevated population of apoptotic cells.
Comparative effects of di(n-butyl) phthalate exposure on fetal germ cell development in the rat and in human fetal testis xenografts
. Environ Health Perspect 123(3):223-230 (2015); doi: 10.1289/ehp.1408248.
Materials and Methods: We tested VPA for its anti-tumor activity on the human tongue cancer (SAS) cell line in vitro and in vivo in a tumor xenograft
model in mice.
Bachground: Testis tissue xenografting and the resultant sperm in a xenograft
may provide a unique approach to rescue the genetic material of males that die prematurely and is a model for the study of human spermatogenesis and can represent an alternative approach for fertility preservation in cancer patients.
An unrelated Australian study demonstrated that it's possible to generate xenografts
of the earlier low to moderate grade, localized tumors (Nat.