juvenile xanthogranuloma

(redirected from Xanthogranuloma, juvenile)


a tumor having histologic characteristics of both granuloma and xanthoma.
juvenile xanthogranuloma a benign, self-limited disorder of infants and children, usually present at birth, manifested by the development of single or multiple papules or nodules, which may be yellow, pink, orange, or reddish brown in color, found typically on the scalp, face, proximal extremities, or trunk; involvement of mucous membranes, viscera, eye, and other organs may also occur.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ju·ve·nile xan·tho·gran·u·lo·ma

single or multiple reddish to yellow papules or nodules, usually found in young children, consisting of dermal infiltration by histiocytes and Touton giant cells, with increasing fibrosis.
Farlex Partner Medical Dictionary © Farlex 2012

juvenile xanthogranuloma

Juvenile lipogranuloma, nevoxanthoendothelioma A yellowish tumor of early childhood, involving the face, head, neck, extremities Prognosis Spontaneous involution
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

xanthogranuloma, juvenile (JXG) 

A benign proliferation of single or multiple, small yellowish-brown papules or nodules in the skin and the anterior uvea, especially the iris. The condition mainly appears in young children, although it may occur in adults. The lesions consist of dermal infiltration by histiocytes, lymphocytes, eosinophils and Touton giant cells. The skin lesions increase in size and number but eventually regress spontaneously into an atrophic scar, otherwise they may need to be treated by excision or corticosteroid injection. In the eye it is commonly associated with hyphaemia (in the anterior chamber), uveitis and secondary glaucoma with visual loss. Therapy includes topical and systemic corticosteroids. Syn. juvenile nevoxanthoendothelioma.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann