xanthine oxidase

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xan·thine ox·i·dase

a flavoprotein containing molybdenum; an oxidoreductase catalyzing the reaction of xanthine, O2, and H2O to produce urate and superoxide. Also oxidizes hypoxanthine, some other purines and pterins, and aldehydes. A lower rate of oxidation is observed in patients with molybdenum cofactor deficiency.
Farlex Partner Medical Dictionary © Farlex 2012

xan·thine ox·i·dase

(zanthēn oksi-dās)
Flavoprotein containing molybdenum; also oxidizes hypoxanthine, some other purines and pterins, and aldehydes.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


Franz, Austrian scientist, 1853-1920.
Schardinger dextrins - the result of action of Bacillus macerans on starch.
Schardinger enzyme - a flavoprotein containing molybdenum. Synonym(s): xanthine oxidase
Schardinger reaction - an example of oxidation in the absence of O2 with an organic hydrogen acceptor.
Medical Eponyms © Farlex 2012
References in periodicals archive ?
Purification and partial characterisation of camel milk xanthine oxidoreductase. Archives of Physiology and Biochemistry 111(5): 407- 414.
Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase. Journal of Biological Chemistry 275: 7757-7763.
Ahluwalia, ""Repurposing" of xanthine oxidoreductase as a nitrite reductase: a new paradigm for therapeutic targeting in hypertension," Antioxidants & Redox Signaling, vol.
Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications.
Proinflammatory Activity of Xanthine Oxidoreductase Products
Xanthine oxidoreductase in atherosclerosis pathogenesis: Not only oxidative stress.
Rathod et al., "Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase," Circulation Research, vol.
Nampei et al., "Effects of topiroxostat and febuxostat on urinary albumin excretion and plasma xanthine oxidoreductase activity in db/db mice," European Journal of Pharmacology, vol.
XO activity was measured as xanthine oxidoreductase (XOR) activity using a method described previously [35].
Nishino et al., "Y-700 [1-[3-Cyano4-(2,2- dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion," Journal of Pharmacology and Experimental Therapeutics, vol.