xanthine oxidase

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xan·thine ox·i·dase

a flavoprotein containing molybdenum; an oxidoreductase catalyzing the reaction of xanthine, O2, and H2O to produce urate and superoxide. Also oxidizes hypoxanthine, some other purines and pterins, and aldehydes. A lower rate of oxidation is observed in patients with molybdenum cofactor deficiency.

xanthine oxidase

/xan·thine ox·i·dase/ (ok´sĭ-dās) a flavoprotein enzyme that catalyzes the oxidation of hypoxanthine to xanthine and then to uric acid, the final steps in the degradation of purines; deficiency, an autosomal recessive trait, causes xanthinuria.

xan·thine ox·i·dase

(zanthēn oksi-dās)
Flavoprotein containing molybdenum; also oxidizes hypoxanthine, some other purines and pterins, and aldehydes.

Schardinger,

Franz, Austrian scientist, 1853-1920.
Schardinger dextrins - the result of action of Bacillus macerans on starch.
Schardinger enzyme - a flavoprotein containing molybdenum. Synonym(s): xanthine oxidase
Schardinger reaction - an example of oxidation in the absence of O2 with an organic hydrogen acceptor.

xanthine

a purine compound found in most bodily tissues and fluids; it is a precursor of uric acid. Xanthine compounds such as theophylline have diuretic properties.

xanthine calculi
see xanthine urolith.
dimethyl xanthine
theobromine.
xanthine oxidase
key enzyme in the pathway for purine breakdown. Catalyzes the conversion of hypoxanthine to xanthine and then to uric acid. Generates hydrogen peroxide, which can be a generator of free radicals in biological systems through reactions with superoxide ions.
trimethyl xanthine
caffeine.
References in periodicals archive ?
Intermediate dehydrogenase oxidase form of xanthine oxidoreductase in rat liver.
Like iron, copper, zinc, manganese, and cobalt, molybdenum (Mo) can be utilized as a stably bound, variably coordinated cofactor in proteins, in mammals, Mo is found in three different enzymes: aldehyde oxidoreductase (AOR), sulfite oxidase (SOX), and xanthine oxidoreductase (XOR).
This study aimed to assess relations between xanthine serum xanthine oxidoreductases, uric acid and trace elements (Mo and Fe) in sera of cholelithiasis patients.
Proinflammatory Activity of Xanthine Oxidoreductase Products
Pro- and Antitumorigenic Activity of Xanthine Oxidoreductase Products
Xanthine Oxidoreductase activity in sera was determined by the method of Ackermann and Brill "as discussed by Ackermann (1974)" and Serum uric acid level was measured by enzymatic end point method supplied by Spinreact.
Purification and partial characterisation of camel milk xanthine oxidoreductase.
Enhanced Expression and Activity of Xanthine Oxidoreductase in the Failing Heart.
Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions.
Administration of adenosine before irradiation ameliorated xanthine oxidoreductase system and protected uric acid values.