xeroderma pigmentosum complementation group B

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xeroderma pigmentosum complementation group B

An autosomal recessive pigmentary skin disorder (OMIM:610651) characterised by photosensivity of the skin, high risk of cancer on sun-exposed skin and, in some cases, neurologic defects. Some XPB patients have features of Cockayne syndrome, i.e., dwarfism, sensorineural deafness, microcephaly, mental retardation, pigmentary retinopathy, ataxia and decreased nerve conduction velocities.

Molecular pathology
Defects of ERCC3, which encodes a protein involved in nucleotide excision repair (NER) of DNA and in RNA transcription, cause xeroderma pigmentosum complementation group B.
References in periodicals archive ?
Caption: 2 3/4%-inch group from the Taurus 605 using Barnes XPB HP.
"XPB 446 has very good optical density, slightly better than Special Black 250," said Thomas Powell, technical market manager, Orion Engineered Carbons.
Tainer, "XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase," DNA Repair, vol.
In polyurethane coatings, XPB 255 displays very high jetness and strong bluish undertones, which can be further maximized by using dispersion additives and optimizing the total quantity of XPB 255 in the mill base and final lacquer.
The Hornady 240- and 300-grain XTP-Mag bullets are also quite good, as is the 250-grain XPB from Barnes.
Following the final implementation of a similar system on a P&H4100 XPB in 2012, Teck staff recognized the benefits of this innovative payload monitoring system together with its interactive server database, allowing personnel to easily analyze health, production and payload data.
To convince themselves that the interaction between triplotide and XPB is what stops cells from growing, the researchers made 12 chemicals related to triplotide with a wide range of activity and treated HeLa cells with each of the 12 chemicals at several different doses.
The role of XPB in cell apoptosis and viability and its relationship with p53, p21(wafl/cipl) and c-myc in hepatoma cells.
The XPB is a hybrid-cam bow powered by a Twin Track Binary System that delivers IBO speeds of 320-324 fps.
Black American women have triple the risk of an early preterm birth (EPB) and four times the risk of an extremely preterm birth (XPB) as non-black American women.