AdRP represents 15-20% of all cases of RP, arRP comprises 20-25% of cases and the X-linked recessive
type makes up 10-15% of cases.
However, based on pedigree analysis, X-linked recessive
inheritance is most likely, which is similar to the recent report of clustering in a family.
G2P-hex also effectively describes why dominant mode does not skip any generation (because all kinds of parent unions involving at least one affected allele result in affected offspring) whereas recessive mode tend to skip generations (because of possibility of producing all normal offspring though carriers of disease in 0-1 and 0-2 parent unions in autosomal recessive and F1-M0 union in X-linked recessive
Mutations in the dystrophin (Duchenne muscular dystrophy [ DMD ]) gene, which encodes a protein connecting the cytoskeleton of muscle fibers, result in X-linked recessive
dystrophinopathy, including DMD and Becker muscular dystrophy (BMD).
He published work in the New England Journal of Medicine focused on X-linked recessive
mutations and male infertility.
Osteopetrosis can be inherited in an AD, autosomal recessive (AR), or X-linked recessive
(XR) manner (2).
Glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency) also known as "favism" is an X-linked recessive
genetic condition that predisposes to hemolysis1 and resultant jaundice in response to triggers, such as hypoxia, certain foods, illness and medication2.
2) Certain anatomical abnormalities of the urinary tract and specific drugs can increase the chances of stone formation; and, finally, there are several inherited disorders predisposing individuals metabolically to nephrolithiasis such as autosomal recessive cystinuria and X-linked recessive
The disease has an X-linked recessive
pattern of inheritance and results from IKBKG gene-NF-kB signaling abnormality.
It is an X-linked recessive
disorder, which is more prevalent in males than in females.
1) The inheritance can be autosomal dominant, autosomal recessive or X-linked recessive
Juvenile X-linked retinoschisis is an inherited disorder transmitted as an X-linked recessive
trait and thus affecting males almost exclusively.