Chromosome X carries the loci for the XK protein (bears the Kx antigen) and for the rare X-linked disorder
that leads to McLeod syndrome found only in males.
IP is an X-linked disorder
involving mainly female neonate.
Despite the fact that Fabry disease is an X-linked disorder
, several female heterozygote mutation carriers have distinct clinical symptoms.
It is therefore classified as leukodystrophy and is inherited as an X-linked disorder
caused by a defect in myelination.
Incontinentia pigmenti is X-linked disorder
affecting Skin, Hair, Teeth and Central Nervous System.
Choroideremia is an X-linked disorder
, which means that it is caused by a faulty gene, called CHM, on the X chromosome.
(7) However, two of the best-described forms of Kallman syndrome are inherited autosomal dominant and X-linked disorder
. (7) An obvious problem with this diagnosis is the healthy father, although it cannot be fully rejected because the phenotype of these patients varies from partial to complete.
Hemophilia B is an X-linked disorder
resulting from a defect in the gene encoding human factor IX (FIX).
However, rare features included no spinal cord involvement and no family history of males with spinal cord disease or AMN (since this disease is X-linked disorder
), though 5% may occur by de novo mutation (7).
The X-linked disorder
was first recognized in 1966 by the late Viennese physician Dr.
Classic haemophilia is an X-linked disorder
, with either a deficiency of factor VIII (haemophilia A), or of factor IX (haemophilia B) being inherited from the mother.